Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.30 |
| ▸ | KAT2A | Q92830 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11196525 | 0.73 | CYP2C19 (0.36) | GBA1CYP2C19 | |
| SCHEMBL1635419 | 0.70 | UGT2B7 (0.33) | GBA1CYP2C19 | |
| SCHEMBL15362595 | 0.70 | KAT2A (0.34) | SLC1A2KAT2A | |
| SCHEMBL6268367 | 0.70 | UGT2B7 (0.33) | GBA1CYP2C19 | |
| SCHEMBL1633940 | 0.67 | UGT2B7 (0.33) | GBA1 | |
| SCHEMBL16969453 | 0.67 | OPRM1 (0.33) | GBA1 | |
| SCHEMBL10776004 | 0.67 | UGT2B7 (0.35) | — | |
| SCHEMBL10776006 | 0.67 | UGT2B7 (0.35) | — | |
| SCHEMBL11009300 | 0.65 | — | — | |
| SCHEMBL11004398 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558230-B1 | SPIROCYCLOPROPYL AMIDES AND ACIDS AND THEIR THERAPEUTIC APPLICATIONS | ABBOTT LAB (US) | 2008-12-31 | — | — | EP | disclosed |