Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B7 | P16662 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1635419 | 1.00 | UGT2B7 (0.33) | UGT2B7CYP2C19GBA1APLNR | |
| SCHEMBL1633940 | 0.98 | UGT2B7 (0.33) | UGT2B7GBA1APLNR | |
| SCHEMBL11196525 | 0.80 | CYP2C19 (0.36) | UGT2B7CYP2C19GBA1 | |
| SCHEMBL1635111 | 0.80 | EPHX1 (0.34) | — | |
| SCHEMBL1634436 | 0.77 | EPHX1 (0.35) | — | |
| SCHEMBL1635709 | 0.72 | ALDH1A1 (0.51) | — | |
| SCHEMBL4663145 | 0.70 | SLC1A2 (0.32) | CYP2C19GBA1 | |
| SCHEMBL11472747 | 0.70 | LMNA (0.34) | UGT2B7GBA1 | |
| SCHEMBL4660443 | 0.68 | APLNR (0.31) | CYP2C19APLNR | |
| SCHEMBL11009300 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592661-A2 | CYCLOPROPYL BETA-AMINO ACID DERIVATIVES | Warner-Lambert Company LLC (US) | 2005-11-09 | — | — | EP | claimed |
| WO-2004065361-A2 | CYCLOPROPYL BETA-AMINO ACID DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2004-08-05 | — | — | WO | claimed |
| EP-1592661-A2 | CYCLOPROPYL BETA-AMINO ACID DERIVATIVES | Warner-Lambert Company LLC (US) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004065361-A2 | CYCLOPROPYL BETA-AMINO ACID DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2004-08-05 | — | — | WO | disclosed |