Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1633449 | 0.79 | HSD11B1 (0.47) | HSD11B1 | |
| SCHEMBL1636848 | 0.79 | HSD11B1 (0.47) | HSD11B1 | |
| SCHEMBL1633448 | 0.79 | HSD11B1 (0.47) | HSD11B1 | |
| SCHEMBL1784428 | 0.71 | HSD11B1 (0.31) | HSD11B1 | |
| SCHEMBL1636662 | 0.71 | EPHX1 (0.40) | HSD11B1 | |
| SCHEMBL11665887 | 0.69 | HSD11B1 (0.34) | HSD11B1 | |
| SCHEMBL20897002 | 0.69 | HSD11B1 (0.32) | HSD11B1 | |
| SCHEMBL1635194 | 0.69 | MAPT (0.38) | HSD11B1MAPT | |
| SCHEMBL29112277 | 0.68 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL29682105 | 0.68 | HSD11B1 (0.33) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558230-B1 | SPIROCYCLOPROPYL AMIDES AND ACIDS AND THEIR THERAPEUTIC APPLICATIONS | ABBOTT LAB (US) | 2008-12-31 | — | — | EP | claimed |