Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29682105 | 1.00 | HSD11B1 (0.33) | HSD11B1CYP1A2EPHX1TRPV1 | |
| SCHEMBL7978200 | 1.00 | HSD11B1 (0.33) | HSD11B1CYP1A2EPHX1TRPV1 | |
| SCHEMBL30626433 | 0.84 | EPHX1 (0.39) | HSD11B1EPHX1TRPV1 | |
| SCHEMBL305653 | 0.84 | EPHX1 (0.39) | HSD11B1EPHX1TRPV1 | |
| SCHEMBL29112414 | 0.84 | EPHX1 (0.39) | HSD11B1EPHX1TRPV1 | |
| Lactic Acid SCHEMBL306590 | 0.80 | EPHX1 (0.34) | EPHX1 | |
| SCHEMBL11232712 | 0.80 | HSD11B1 (0.32) | HSD11B1 | |
| SCHEMBL11665887 | 0.79 | HSD11B1 (0.34) | HSD11B1CYP1A2EPHX1TRPV1 | |
| SCHEMBL29681945 | 0.78 | ALDH1A1 (0.33) | CYP1A2 | |
| SCHEMBL31253748 | 0.77 | EPHX1 (0.31) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829532-A | Substituted cyclohexane carboxamides, their preparation and their therapeutic use | 赛诺菲 | 2023-09-29 | — | — | CN | disclosed |