Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15575892 | 0.76 | — | — | |
| SCHEMBL1038873 | 0.76 | — | — | |
| SCHEMBL7972 | 0.73 | MEN1 (0.31) | AURKAAURKBINCENP | |
| SCHEMBL3152148 | 0.69 | LMNA (0.35) | — | |
| SCHEMBL1707247 | 0.68 | KDM4E (0.31) | AURKAAURKBINCENP | |
| SCHEMBL2962726 | 0.67 | MCL1 (0.42) | AURKAAURKBINCENP | |
| SCHEMBL1351786 | 0.66 | COMT (0.48) | — | |
| SCHEMBL10370901 | 0.65 | AURKA (0.34) | AURKAAURKBINCENP | |
| SCHEMBL27607780 | 0.64 | CYP3A4 (0.48) | — | |
| SCHEMBL27969159 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819133-B1 | COVALENTLY LINKED OLIGONUCLEOTIDE MINOR GROOVE BINDER CONJUGATES | EPOCH BIOSCIENCES INC (US) | 2008-01-02 | — | — | EP | claimed |
| CN-106220615-A | Pyrazoles aminopyridine derivative as LRRK2 regulator | 霍夫曼-拉罗奇有限公司 | 2016-12-14 | — | — | CN | disclosed |
| CN-104271569-B | Pyrazolylaminopyrimidine derivatives as LRRK2 modulators | 霍夫曼-拉罗奇有限公司 | 2016-08-24 | — | — | CN | disclosed |