SCHEMBL4663209

SCHEMBL4663209

Cc1ccc(C(=O)Nc2ccc(N3CCOC3=N)cc2)c(N(CS(=O)(=O)O)C(=O)c2ccc(Cl)s2)c1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
F10 P00742 13/20 0.42
MAPT P10636 3/20 0.39
KMT2A Q03164 3/20 0.39
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 2/20 0.39
HTT P42858 2/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
KDM4E B2RXH2 1/20 0.36
GLA P06280 1/20 0.36
MCL1 Q07820 1/20 0.36
LMNA P02545 1/20 0.35
RECQL P46063 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4667932 0.92 F10 (0.43) F10MAPTKMT2AALDH1A1MEN1
SCHEMBL4665046 0.91 F10 (0.42) F10MAPTKMT2AALDH1A1MEN1
SCHEMBL4665199 0.90 F10 (0.40) F10MAPTKMT2AALDH1A1MEN1
SCHEMBL4666914 0.90 F10 (0.48) F10MAPTKMT2AALDH1A1MEN1
SCHEMBL4667334 0.90 F10 (0.50) F10MAPTKMT2AALDH1A1MEN1
SCHEMBL4632548 0.89 F10 (0.40) F10MAPTKMT2AALDH1A1MEN1
SCHEMBL4665290 0.89 F10 (0.40) F10MAPTKMT2AALDH1A1MEN1
SCHEMBL4667573 0.89 F10 (0.40) F10MAPTKMT2AALDH1A1MEN1
SCHEMBL4663518 0.88 F10 (0.39) F10MAPTKMT2AALDH1A1MEN1
SCHEMBL4632553 0.87 F10 (0.43) F10MAPTKMT2AALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1928868-A1 IMINOOXAZOLIDINE DERIVATIVES AND USE THEREOF Bayer HealthCare AG (DE) 2008-06-11 EP disclosed
WO-2007028520-A1 IMINOOXAZOLIDINE DERIVATIVES AND USE THEREOF BAYER HEALTHCARE AG (DE) 2007-03-15 WO disclosed