Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4667932 | 0.92 | F10 (0.43) | F10MAPTHTTMEN1ALDH1A1 | |
| SCHEMBL4663209 | 0.91 | F10 (0.42) | F10MAPTHTTMEN1ALDH1A1 | |
| SCHEMBL4665199 | 0.90 | F10 (0.40) | F10MAPTHTTMEN1ALDH1A1 | |
| SCHEMBL4665290 | 0.90 | F10 (0.40) | F10MAPTHTTMEN1ALDH1A1 | |
| SCHEMBL4667334 | 0.90 | F10 (0.50) | F10MAPTHTTMEN1ALDH1A1 | |
| SCHEMBL4666914 | 0.89 | F10 (0.48) | F10MAPTHTTMEN1ALDH1A1 | |
| SCHEMBL4667573 | 0.89 | F10 (0.40) | F10MAPTHTTMEN1ALDH1A1 | |
| SCHEMBL4632553 | 0.87 | F10 (0.43) | F10MAPTHTTMEN1ALDH1A1 | |
| SCHEMBL4632548 | 0.86 | F10 (0.40) | F10MAPTHTTMEN1ALDH1A1 | |
| SCHEMBL3617560 | 0.85 | F10 (0.46) | F10MAPTHTTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928868-A1 | IMINOOXAZOLIDINE DERIVATIVES AND USE THEREOF | Bayer HealthCare AG (DE) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007028520-A1 | IMINOOXAZOLIDINE DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2007-03-15 | — | — | WO | disclosed |