SCHEMBL4663349

SCHEMBL4663349

CC(C)CC(C)(OOC(=O)c1ccc(C(=O)c2ccccc2)cc1)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.51
TDP1 Q9NUW8 2/20 0.51
TSHR P16473 1/20 0.51
HSD17B10 Q99714 1/20 0.51
F2 P00734 1/20 0.41
LMNA P02545 1/20 0.41
ELANE P08246 9/20 0.40
RAB9A P51151 2/20 0.39
PPARA Q07869 1/20 0.39
GAA P10253 1/20 0.38
HTT P42858 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MAPT P10636 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HPGD P15428 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37
MMP1 P03956 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5491740 0.85 ALDH1A1 (0.38) ALDH1A1TDP1TSHRHSD17B10LMNA
SCHEMBL28914386 0.77 TDP1 (0.60) ALDH1A1TDP1TSHRHSD17B10F2
SCHEMBL20457633 0.77 ALDH1A1 (0.53) ALDH1A1TDP1TSHRHSD17B10F2
SCHEMBL1660474 0.77 TDP1 (0.86) ALDH1A1TDP1TSHRHSD17B10F2
SCHEMBL481608 0.76 MAPK1 (0.46) ALDH1A1HSD17B10GAASMN1; SMN2CYP2D6
Benzophenone SCHEMBL10622042 0.75 TDP1 (0.89) ALDH1A1TDP1TSHRHSD17B10F2
SCHEMBL28039492 0.73 TDP1 (0.54) ALDH1A1TDP1TSHRHSD17B10F2
SCHEMBL11491766 0.72 TSHR (0.53) ALDH1A1TDP1TSHRHSD17B10F2
SCHEMBL11491762 0.72 TSHR (0.53) ALDH1A1TDP1TSHRHSD17B10F2
SCHEMBL6659565 0.72 TDP1 (0.70) ALDH1A1TDP1TSHRHSD17B10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0520364-B1 Photopolymerizable composition FUJI PHOTO FILM CO LTD (JP) 1997-09-17 EP claimed
CN-108698427-B Cylindrical printing plate, cylindrical printing plate precursor, and method for producing same 富士胶片株式会社 2020-01-14 CN disclosed
US-20150197079-A1 PROCESS FOR PRODUCING CYLINDRICAL PRINTING PLATE PRECURSOR, CYLINDRICAL PRINTING PLATE AND PROCESS FOR MAKING SAME FUJIFILM CORPORATION (JP) 2015-07-16 US disclosed
EP-1449651-B1 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORP (JP) 2008-10-29 EP disclosed
US-20080184930-A1 INK-JET RECORDING DEVICE FUJIFILM CORPORATION (JP) 2008-08-07 US disclosed
US-20060005725-A1 Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO., LTD. 2006-01-12 US disclosed
US-6858373-B2 Photosensitive composition and negative working lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 2005-02-22 US disclosed
US-20030091933-A1 Photosensitive composition and negative working lithographic printing plate FUJIFILM CORPORATION (JP) 2003-05-15 US disclosed