Hexythiazox

Hexythiazox

SCHEMBL4663360

C[C@H]1[C@H](c2ccc(Cl)cc2)SC(=O)N1C(=O)NC1CCCCC1.C[C@H]1[C@H](c2ccc(Cl)cc2)SC(=O)N1C(=O)NC1CCCCC1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
LMNA P02545 1/20 0.45
HTT P42858 1/20 0.45
EPHX1 P07099 3/20 0.43
POLB P06746 1/20 0.43
NPC1 O15118 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
RAB9A P51151 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
CNR1 P21554 8/20 0.42
CNR2 P34972 4/20 0.41
ALOX12 P18054 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexythiazox SCHEMBL53695 1.00 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2LMNAHTTEPHX1
SCHEMBL11108861 1.00 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2LMNAHTTEPHX1
SCHEMBL11108858 1.00 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2LMNAHTTEPHX1
Hexythiazox SCHEMBL21175552 1.00 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2LMNAHTTEPHX1
SCHEMBL11108860 1.00 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2LMNAHTTEPHX1
Hexythiazox SCHEMBL53694 1.00 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2LMNAHTTEPHX1
Hexythiazox SCHEMBL1651194 1.00 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2LMNAHTTEPHX1
Hexythiazox SCHEMBL3960887 0.99 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2LMNAHTTEPHX1
Hexythiazox SCHEMBL2554460 0.99 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2LMNAHTTEPHX1
SCHEMBL11110824 0.91 KMT2A (0.44) ALDH1A1SMN1; SMN2LMNAHTTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1896045-B1 COMPOSITION COMPRISING BRASSICACEA SEEDS MEAL AND THEIR USE AS BIOPESTICIDES IN PLANTS RONGAI DOMENICO (IT) 2016-08-17 EP disclosed
US-20080199451-A1 Composition for the Treatment and/or Prevention of Attacks by Biological Agents RONGAI DOMENICO 2008-08-21 US disclosed
EP-1896045-A2 COMPOSITION FOR THE TREATMENT AND/OR PREVENTION OF ATTACKS BY BIOLOGICAL AGENTS Rongai, Domenico (IT) 2008-03-12 EP disclosed
WO-2006136933-A2 COMPOSITION FOR THE TREATMENT AND/OR PREVENTION OF ATTACKS BY BIOLOGICAL AGENTS RONGAI DOMENICO (IT) 2006-12-28 WO disclosed
EP-0920637-A4 NAVIGATION SYSTEM AND METHOD GREENFIELD ENTPR INC (US) 2002-05-29 EP disclosed
US-5912208-A NONIONIC SURFACTANTS OF GLYCEROL-BASED POLYETHER HAVING A POTENTIATING EFFECT ON BACTERICIDES, INSECTICIDES, MITICIDES, HERBICIDES AND PLANT GROWTH REGULATORS; NO CHEMICAL DAMAGE WHEN A MIXTURE IS APPLIED TO CROPS KAO CORPORATION (JP) 1999-06-15 US disclosed
EP-0920637-A2 NAVIGATION SYSTEM AND METHOD Greenfield Enterprises Inc. (US) 1999-06-09 EP disclosed
EP-0920637-A3 NAVIGATION SYSTEM AND METHOD Greenfield Enterprises Inc. (US) 1999-01-21 EP disclosed
WO-1998048292-A2 NAVIGATION SYSTEM AND METHOD GREENFIELD ENTERPRISES, INC. (US) 1998-10-29 WO disclosed
US-5728649-A CATIONIC SURFACTANTS FOR AGRICULTURE KAO CORPORATION (JP) 1998-03-17 US disclosed
US-5538937-A FOR USE WITH HERBICIDES, PESTICIDES, PLANT GROWTH REGULATORS, IMPROVED EFFECTIVENESS HASEBE KEIKO (JP) 1996-07-23 US disclosed