Hexythiazox

Hexythiazox

SCHEMBL21175552

C[C@H]1C(c2ccc(Cl)cc2)SC(=O)N1C(=O)NC1CCCCC1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
LMNA P02545 1/20 0.45
HTT P42858 1/20 0.45
EPHX1 P07099 3/20 0.43
POLB P06746 1/20 0.43
NPC1 O15118 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
RAB9A P51151 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
CNR1 P21554 8/20 0.42
CNR2 P34972 4/20 0.41
ALOX12 P18054 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexythiazox SCHEMBL53695 1.00 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2LMNAHTTEPHX1
SCHEMBL11108861 1.00 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2LMNAHTTEPHX1
SCHEMBL11108858 1.00 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2LMNAHTTEPHX1
Hexythiazox SCHEMBL4663360 1.00 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2LMNAHTTEPHX1
SCHEMBL11108860 1.00 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2LMNAHTTEPHX1
Hexythiazox SCHEMBL53694 1.00 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2LMNAHTTEPHX1
Hexythiazox SCHEMBL1651194 1.00 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2LMNAHTTEPHX1
Hexythiazox SCHEMBL3960887 0.99 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2LMNAHTTEPHX1
Hexythiazox SCHEMBL2554460 0.99 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2LMNAHTTEPHX1
SCHEMBL11110824 0.91 KMT2A (0.44) ALDH1A1SMN1; SMN2LMNAHTTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023203038-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2023-10-26 WO claimed
US-12325646-B2 Fertigation water treatment UNIVERSITY OF GUELPH (CA) 2025-06-10 US disclosed
US-20250024837-A1 PESTICIDE SYSTEM BANISH, MICHELE 2025-01-23 US disclosed
WO-2023203038-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2023-10-26 WO disclosed
US-20230120480-A1 METHODS FOR REMOVING CONTAMINANTS FROM PLANT-DERIVED PHARMACEUTICALS SORBENT TECHNOLOGIES, INC. 2023-04-20 US disclosed
CN-111978271-B Hexythiazox hapten and preparation method thereof, hexythiazox antigen, antibody and application thereof 重庆市农业科学院 2022-08-30 CN disclosed
US-20220234916-A1 WATER TREATMENT UNIVERSITY OF GUELPH (CA) 2022-07-28 US disclosed
US-20220104496-A1 PESTICIDALLY ACTIVE BI- OR TRICYCLIC HETEROCYCLES WITH SULFUR CONTAINING SUBSTITUENTS SYNGENTA PARTICIPATIONS AG (CH) 2022-04-07 US disclosed
US-20220015358-A1 Encapsulated Biocides ARXADA AG (CH) 2022-01-20 US disclosed
US-11169128-B2 Electronic ID database and detection method for pesticide compound in edible agro-products based on LC-Q-Orbitrap CHINESE ACADEMY OF INSPECTION AND QUARANTINE 2021-11-09 US disclosed
US-20210341440-A1 Systems and Methods for Pesticide Detection PERKINELMER U.S. LLC 2021-11-04 US disclosed
CN-113226026-A Encapsulated fungicides 隆萨解决方案股份公司 2021-08-06 CN disclosed
US-20210223219-A1 ELECTRONIC ID DATABASE AND DETECTION METHOD FOR PESTICIDE COMPOUND IN EDIBLE AGRO-PRODUCTS BASED ON LC-Q-ORBITRAP BEIJING UNI-STAR INSPECTION TECHNOLOGY CO., LTD. (CN) 2021-07-22 US disclosed
US-20210181182-A1 METHOD FOR IDENTIFICATION OF PERTURBAGENS OF PARTICULAR BIOLOGICAL PROCESSES AND CELL SYSTEMS WITHIN LIVING CELLS ATTAGENE INC (US) 2021-06-17 US disclosed
US-11026985-B2 Methods for removing contaminants from plant-derived pharmaceuticals SORBENT TECHNOLOGIES, INC. (US) 2021-06-08 US disclosed
US-10914713-B2 Systems and methods for pesticide detection using mass spectroscopy PERKINELMER HEALTH SCIENCES, INC. (US) 2021-02-09 US disclosed
CN-111978271-A Hexythiazox hapten and preparation method thereof, hexythiazox antigen, antibody and application thereof 重庆市农业科学院 2020-11-24 CN disclosed
US-20200093876-A1 METHODS FOR REMOVING CONTAMINANTS FROM PLANT-DERIVED PHARMACEUTICALS SORBENT TECHNOLOGIES, INC. 2020-03-26 US disclosed
US-20190227041-A1 Systems and Methods for Pesticide Detection PERKINELMER U.S. LLC 2019-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220104496-A1 PESTICIDALLY ACTIVE BI- OR TRICYCLIC HETEROCYCLES WITH SULFUR CONTAINING SUBSTITUENTS GSTA1, CYP1B1, DDT ALDH1A1 149/4885SMN1; SMN2 1906/4885LMNA 2366/4885
US-11026985-B2 Methods for removing contaminants from plant-derived pharmaceuticals CES2, CNR2, GUSB ALDH1A1 1215/4885SMN1; SMN2 4407/4885LMNA 4184/4885
US-20250024837-A1 PESTICIDE SYSTEM ACHE, PFAS, FPGS ALDH1A1 3501/4885SMN1; SMN2 4407/4885LMNA 3099/4885
US-20230120480-A1 METHODS FOR REMOVING CONTAMINANTS FROM PLANT-DERIVED PHARMACEUTICALS CES2, CNR2, GUSB ALDH1A1 1215/4885SMN1; SMN2 4407/4885LMNA 4184/4885
US-20220015358-A1 Encapsulated Biocides PCBP1, PUF60, PNN ALDH1A1 1025/4885SMN1; SMN2 2794/4885LMNA 2194/4885
US-20200093876-A1 METHODS FOR REMOVING CONTAMINANTS FROM PLANT-DERIVED PHARMACEUTICALS CES2, CNR2, GUSB ALDH1A1 1215/4885SMN1; SMN2 4407/4885LMNA 4184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.