SCHEMBL4664060

SCHEMBL4664060

C1CN([PH](N2CCOCC2)(N2CCOCC2)N2CCOCC2)CCO1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.40
CA12 O43570 4/20 0.36
CA7 P43166 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA1 P00915 3/20 0.33
CA9 Q16790 3/20 0.33
CA2 P00918 2/20 0.33
TTR P02766 1/20 0.33
SMN1; SMN2 Q16637 3/20 0.32
ALDH1A1 P00352 2/20 0.32
FAAH O00519 1/20 0.32
PHGDH O43175 1/20 0.32
ALDH2 P05091 1/20 0.32
PDK1 Q15118 1/20 0.32
PDK2 Q15119 1/20 0.32
PDK3 Q15120 1/20 0.32
USP2 O75604 1/20 0.32
TSHR P16473 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KEAP1 Q14145 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23312360 0.73 MGLL (0.36) MGLLCA12CA7CA14CA1
SCHEMBL359471 0.71 MGLL (0.40) MGLLCA12CA7CA14CA1
SCHEMBL3366801 0.69 CA12 (0.33) MGLLCA12CA7CA14CA1
SCHEMBL20091636 0.67 USP2 (0.38) MGLLCA12CA1CA9CA2
SCHEMBL27434947 0.67
SCHEMBL27985708 0.67
SCHEMBL23312354 0.66 PDK1 (0.34) MGLLSMN1; SMN2ALDH1A1PDK1PDK2
SCHEMBL236146 0.65 MGLL (0.47) MGLLCA12CA7CA14CA1
SCHEMBL4662395 0.65
SCHEMBL10599432 0.65 MGLL (0.47) MGLLCA12CA7CA14CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1928839-B1 METHOD FOR THE PRODUCTION OF 5-FLUORO-1,3-DIALKYL-1H-PYRAZOL-4-CARBONYL FLUORIDES BAYER CROPSCIENCE AG (DE) 2008-12-31 EP claimed
EP-0958052-B1 AMIDOPHOSPHONIUM-SALT-CONTAINING CATALYST FOR HALOGEN-FLUORINE EXCHANGE REACTIONS CLARIANT GMBH (DE) 2002-12-04 EP claimed