Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14398049 | 0.83 | GHSR (0.56) | GHSRALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL13245992 | 0.83 | GHSR (0.56) | GHSRALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL13245976 | 0.83 | GHSR (0.56) | GHSRALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL4664122 | 0.82 | ALDH1A1 (0.47) | GHSRALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL4664086 | 0.81 | GHSR (0.58) | GHSRALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL13245971 | 0.80 | ALDH1A1 (0.45) | GHSRALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL4665907 | 0.80 | GHSR (0.48) | GHSRKMT2AMAPTLMNAMEN1 | |
| SCHEMBL13245951 | 0.79 | ALDH1A1 (0.46) | GHSRALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL2996213 | 0.76 | GHSR (0.55) | GHSRALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL2992486 | 0.76 | GHSR (0.55) | GHSRALDH1A1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007716-A1 | ARYL AND HETEROARYL SULPHONAMIDES AS GROWTH HORMONE SECRETAGOGUE RECEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | EP | claimed |
| WO-2007118852-A1 | ARYL AND HETEROARYL SULPHONAMIDES AS GROWTH HORMONE SECRETAGOGUE RECEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 2007-10-25 | — | — | WO | claimed |