Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.46 |
| ▸ | BPTF | Q12830 | 9/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.36 |
| ▸ | SGK1 | O00141 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL4663920 | 0.98 | HTR6 (0.46) | HTR6BPTFEGFRNR1I2SGK1 | |
| Formic Acid SCHEMBL4664240 | 0.95 | HTR6 (0.51) | HTR6BPTFEGFRNR1I2SGK1 | |
| Formic Acid SCHEMBL4663919 | 0.93 | EGFR (0.40) | HTR6BPTFEGFR | |
| Formic Acid SCHEMBL4665783 | 0.93 | HTR6 (0.41) | HTR6BPTFEGFRABL1BCR | |
| Formic Acid SCHEMBL4666142 | 0.92 | HTR6 (0.40) | HTR6BPTFEGFRABL1BCR | |
| Formic Acid SCHEMBL4665774 | 0.91 | BPTF (0.41) | HTR6BPTFEGFR | |
| Formic Acid SCHEMBL4666120 | 0.90 | HTR6 (0.42) | HTR6BPTFEGFRABL1BCR | |
| Formic Acid SCHEMBL4664378 | 0.89 | HTR6 (0.45) | HTR6BPTFEGFRABL1BCR | |
| Formic Acid SCHEMBL4665710 | 0.88 | HTR6 (0.45) | HTR6BPTFEGFR | |
| Formic Acid SCHEMBL4665819 | 0.88 | HTR6 (0.46) | HTR6BPTFEGFRABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | ALTANA PHARMA AG (DE) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | MAP3K19, MAP3K6, MAP3K20 | HTR6 826/4885BPTF 2862/4885EGFR 279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.