Formic Acid

Formic Acid

SCHEMBL4666142

CCN(CC)CCCCn1ccc2cc(-c3cc(Nc4ccc(NS(=O)(=O)c5ccc(C)cc5F)cc4)ncn3)ccc21.O=CO

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 4/20 0.40
BPTF Q12830 10/20 0.39
EGFR P00533 2/20 0.37
RORC P51449 1/20 0.35
SCN9A Q15858 1/20 0.34
PRF1 P14222 1/20 0.33
ABL1 P00519 1/20 0.33
BCR P11274 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL4665663 0.95 HTR6 (0.45) HTR6BPTFEGFRRORCSCN9A
Formic Acid SCHEMBL4663919 0.94 EGFR (0.40) HTR6BPTFEGFRRORCSCN9A
Formic Acid SCHEMBL4665774 0.92 BPTF (0.41) HTR6BPTFEGFRSCN9APRF1
Formic Acid SCHEMBL4664281 0.92 HTR6 (0.46) HTR6BPTFEGFRABL1BCR
Formic Acid SCHEMBL4663920 0.90 HTR6 (0.46) HTR6BPTFEGFRABL1BCR
Formic Acid SCHEMBL4666201 0.90 BPTF (0.46) HTR6BPTFEGFR
Formic Acid SCHEMBL4665710 0.89 HTR6 (0.45) HTR6BPTFEGFRSCN9APRF1
Formic Acid SCHEMBL4665783 0.89 HTR6 (0.41) HTR6BPTFEGFRSCN9AABL1
Formic Acid SCHEMBL4664378 0.88 HTR6 (0.45) HTR6BPTFEGFRSCN9AABL1
Formic Acid SCHEMBL4666208 0.88 HTR6 (0.46) HTR6BPTFEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080242681-A1 N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors ALTANA PHARMA AG (DE) 2008-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080242681-A1 N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors MAP3K19, MAP3K6, MAP3K20 HTR6 826/4885BPTF 2862/4885EGFR 279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.