SCHEMBL4664473

SCHEMBL4664473

CCN(CC)c1ccc2nc3c4cc(OCCCC(=O)O)ccc4c(=O)c(Br)c-3oc2c1

nearest known ligand 0.72

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ SCP2 P22307 1/20 0.72
▸ GPR84 Q9NQS5 10/20 0.43
▸ MEN1 O00255 1/20 0.42
▸ NPC1 O15118 1/20 0.42
▸ POLB P06746 1/20 0.42
▸ RAB9A P51151 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ ACSL1 P33121 2/20 0.41
▸ ACSL6 Q9UKU0 2/20 0.41
▸ PDE3B Q13370 4/20 0.39
▸ PDE3A Q14432 4/20 0.39
▸ SRC P12931 2/20 0.39
▸ P2RY12 Q9H244 2/20 0.39
▸ PDE2A O00408 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14267415 0.88 SCP2 (0.56) SCP2GPR84MEN1NPC1POLB
SCHEMBL4662802 0.88 SCP2 (0.56) SCP2GPR84MEN1NPC1POLB
SCHEMBL14267417 0.84 SCP2 (1.00) SCP2GPR84MEN1NPC1POLB
SCHEMBL7812704 0.82 SCP2 (0.93) SCP2GPR84MEN1NPC1POLB
SCHEMBL14267412 0.81 MEN1 (0.49) SCP2MEN1NPC1POLBRAB9A
SCHEMBL15398240 0.79 MEN1 (0.64) SCP2MEN1NPC1POLBRAB9A
SCHEMBL4664338 0.78 MEN1 (0.52) SCP2MEN1NPC1POLBRAB9A
SCHEMBL4663120 0.75 MEN1 (0.48) SCP2MEN1NPC1POLBRAB9A
SCHEMBL7815701 0.74 SCP2 (0.79) SCP2GPR84MEN1NPC1POLB
SCHEMBL3501312 0.74 SCP2 (0.82) SCP2GPR84MEN1NPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080038840-A1 Fluorescent Method And Compounds To Monitor Protein-Lipid Binding EUROPAEISCHES LABORATORIUM FUER MOLEKULARBIOLOGIE (DE) 2008-02-14 — — US disclosed
US-20080038840-A1 Fluorescent Method And Compounds To Monitor Protein-Lipid Binding EUROPAEISCHES LABORATORIUM FUER MOLEKULARBIOLOGIE (DE) 2008-02-14 — — US disclosed
US-20080038840-A1 Fluorescent Method And Compounds To Monitor Protein-Lipid Binding EUROPAEISCHES LABORATORIUM FUER MOLEKULARBIOLOGIE (DE) 2008-02-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080038840-A1 Fluorescent Method And Compounds To Monitor Protein-Lipid Binding DBI, CETP, SREBF1 SCP2 34/4885GPR84 1678/4885MEN1 3143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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