Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.44 |
| ▸ | MAPT | P10636 | 9/20 | 0.44 |
| ▸ | GLA | P06280 | 7/20 | 0.44 |
| ▸ | ATM | Q13315 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.44 |
| ▸ | CASP1 | P29466 | 4/20 | 0.44 |
| ▸ | CASP7 | P55210 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14267412 | 0.96 | MEN1 (0.49) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL15398240 | 0.87 | MEN1 (0.64) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL4663120 | 0.85 | MEN1 (0.48) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL14267413 | 0.84 | MEN1 (0.49) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL14267415 | 0.84 | SCP2 (0.56) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL14289862 | 0.82 | KDM4E (0.39) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL4664437 | 0.80 | MEN1 (0.76) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL56792 | 0.78 | MEN1 (0.76) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL14289870 | 0.78 | KDM4E (0.39) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL4664473 | 0.78 | SCP2 (0.72) | MEN1KMT2APOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080038840-A1 | Fluorescent Method And Compounds To Monitor Protein-Lipid Binding | EUROPAEISCHES LABORATORIUM FUER MOLEKULARBIOLOGIE (DE) | 2008-02-14 | — | — | US | disclosed |
| US-20080038840-A1 | Fluorescent Method And Compounds To Monitor Protein-Lipid Binding | EUROPAEISCHES LABORATORIUM FUER MOLEKULARBIOLOGIE (DE) | 2008-02-14 | — | — | US | disclosed |
| US-20080038840-A1 | Fluorescent Method And Compounds To Monitor Protein-Lipid Binding | EUROPAEISCHES LABORATORIUM FUER MOLEKULARBIOLOGIE (DE) | 2008-02-14 | — | — | US | disclosed |
| EP-1595872-A1 | Fluorescent compounds for monitoring protein-lipid binding | EUROPÄISCHES LABORATORIUM FÜR MOLEKULARBIOLOGIE (EMBL) (DE) | 2005-11-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080038840-A1 | Fluorescent Method And Compounds To Monitor Protein-Lipid Binding | DBI, CETP, SREBF1 | MEN1 3143/4885KMT2A 2814/4885POLB 4119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.