Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4664678 | 0.80 | RAB9A (0.65) | MAPTNPY5RALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL6344569 | 0.79 | RAB9A (0.54) | MAPTNPY5RALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL6343068 | 0.79 | CYP1A2 (0.59) | MAPTALDH1A1CYP1A2SMN1; SMN2RAB9A | |
| SCHEMBL13974491 | 0.75 | MAPT (0.43) | MAPTALDH1A1CYP1A2SMN1; SMN2RAB9A | |
| SCHEMBL29406288 | 0.75 | MAPT (0.43) | MAPTALDH1A1CYP1A2SMN1; SMN2RAB9A | |
| SCHEMBL27926117 | 0.74 | SMN1; SMN2 (0.55) | MAPTNPY5RALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL6345119 | 0.74 | NPY5R (0.73) | MAPTNPY5RALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL6452314 | 0.72 | ALDH1A1 (0.47) | MAPTALDH1A1CYP1A2CYP17A1SMN1; SMN2 | |
| SCHEMBL27084518 | 0.72 | MAPT (0.47) | MAPTNPY5RALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL1013458 | 0.72 | MAPT (0.47) | MAPTNPY5RALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928455-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | Bayer Healthcare, LLC (US) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |