Maleic Hydrazide

Maleic Hydrazide

SCHEMBL8367459

NNC(=O)/C=C\C(=O)NN.[NaH]

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.41
TSHR P16473 1/20 0.41
NFKB1 P19838 1/20 0.41
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
THPO P40225 1/20 0.41
LMNA P02545 1/20 0.39
ALDH1A1 P00352 4/20 0.38
GAA P10253 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HIF1A Q16665 1/20 0.33
GFER P55789 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maleic Hydrazide SCHEMBL55070 0.96 CYP1A2 (0.44) CYP1A2TSHRNFKB1MAOAMAOB
Maleic Hydrazide SCHEMBL466482 0.96 CYP1A2 (0.44) CYP1A2TSHRNFKB1MAOAMAOB
Maleic Hydrazide SCHEMBL28265377 0.96 CYP1A2 (0.44) CYP1A2TSHRNFKB1MAOAMAOB
Maleic Hydrazide SCHEMBL1534936 0.96 CYP1A2 (0.44) CYP1A2TSHRNFKB1MAOAMAOB
Maleic Hydrazide SCHEMBL408266 0.93 CYP1A2 (0.41) CYP1A2TSHRNFKB1MAOAMAOB
Maleic Hydrazide SCHEMBL9489247 0.93 CYP1A2 (0.41) CYP1A2TSHRNFKB1MAOAMAOB
Maleic Hydrazide SCHEMBL7116620 0.93 CYP1A2 (0.41) CYP1A2TSHRNFKB1MAOAMAOB
Maleic Hydrazide SCHEMBL30239213 0.93 CYP1A2 (0.41) CYP1A2TSHRNFKB1MAOAMAOB
Maleic Hydrazide SCHEMBL28280739 0.90 CYP1A2 (0.39) CYP1A2TSHRNFKB1MAOAMAOB
SCHEMBL28797787 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103250578-B Method utilizing sprout inhibition agent to control phytoplasma jujube with broom disease and phytoplasma paulownia withes broom disease of plants ZHOU XUESHANG 2015-04-08 CN claimed
CN-103250578-A Method utilizing sprout inhibition agent to control phytoplasma jujube withes broom disease and phytoplasma paulownia withes broom disease of plants ZHOU XUESHANG 2013-08-21 CN claimed
WO-2025078992-A1 METHOD OF CONTROLLING WEEDS UPL MAURITIUS LIMITED (MU) 2025-04-17 WO disclosed
US-20240188560-A1 STABLE EMULSIONS ADAMA AGAN LTD. (IL) 2024-06-13 US disclosed
CN-103250578-B Method utilizing sprout inhibition agent to control phytoplasma jujube with broom disease and phytoplasma paulownia withes broom disease of plants ZHOU XUESHANG 2015-04-08 CN disclosed
CN-103250578-A Method utilizing sprout inhibition agent to control phytoplasma jujube withes broom disease and phytoplasma paulownia withes broom disease of plants ZHOU XUESHANG 2013-08-21 CN disclosed
WO-1999026885-A1 COMPOSITIONS AND METHODS FOR ADSORPTION AND REMEDIATION OF ORGANIC COMPOUNDS UNIVERSITY OF FLORIDA (US) 1999-06-03 WO disclosed
EP-0134339-B1 HERBICIDAL COMPOSITION JAPAN HYDRAZINE CO., LTD. (JP) 1987-10-21 EP disclosed
EP-0134339-A1 Herbicidal composition JAPAN HYDRAZINE CO., LTD. (JP) 1985-03-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240188560-A1 STABLE EMULSIONS POLR2H, POLR2E, PHOSPHO1 CYP1A2 2628/4885TSHR 1862/4885NFKB1 1550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.