Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12343951 | 0.83 | ALDH1A1 (0.46) | ALDH1A1HTTRAB9AMAPTMEN1 | |
| SCHEMBL14705521 | 0.81 | ALDH1A1 (0.45) | ALDH1A1HTTRAB9AMAPTMEN1 | |
| SCHEMBL5115689 | 0.81 | ALDH1A1 (0.45) | ALDH1A1HTTRAB9AMAPTMEN1 | |
| SCHEMBL27608929 | 0.80 | ALDH1A1 (0.44) | ALDH1A1HTTRAB9AMAPTMEN1 | |
| SCHEMBL1982550 | 0.80 | ALDH1A1 (0.44) | ALDH1A1HTTRAB9AMAPTMEN1 | |
| SCHEMBL3329624 | 0.79 | CYP1A2 (0.57) | ALDH1A1HTTRAB9AMAPTMEN1 | |
| SCHEMBL3329616 | 0.79 | CYP1A2 (0.57) | ALDH1A1HTTRAB9AMAPTMEN1 | |
| SCHEMBL4067726 | 0.77 | ALDH1A1 (0.45) | ALDH1A1HTTRAB9AMAPTMEN1 | |
| SCHEMBL13566166 | 0.77 | ALDH1A1 (0.42) | ALDH1A1HTTRAB9AMAPTMEN1 | |
| SCHEMBL3050464 | 0.77 | ALDH1A1 (0.42) | ALDH1A1HTTRAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242685-A1 | Chemical Compounds | SMITHKLINE BEECHAM CORPORATION | 2008-10-02 | — | — | US | disclosed |
| EP-1940296-A2 | CHEMICAL COMPOUNDS | SmithKline Beecham Corporation (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007114848-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242685-A1 | Chemical Compounds | NFKBIA, IKBKG, NFKB2 | ALDH1A1 1519/4885HTT 4420/4885RAB9A 3515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.