Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 17/20 | 0.90 |
| ▸ | CA2 | P00918 | 17/20 | 0.90 |
| ▸ | CA9 | Q16790 | 17/20 | 0.90 |
| ▸ | CA12 | O43570 | 16/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | STS | P08842 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451275 | 0.95 | CA1 (1.00) | CA1CA2CA9CA12STS | |
| SCHEMBL29175683 | 0.81 | CA1 (0.74) | CA1CA2CA9CA12HTT | |
| SCHEMBL5023104 | 0.80 | CA1 (0.72) | CA1CA2CA9CA12HTT | |
| SCHEMBL3818831 | 0.78 | SMN1; SMN2 (1.00) | CA1CA2CA9CA12HTT | |
| SCHEMBL4666145 | 0.78 | STS (0.61) | CA1CA2CA9CA12STS | |
| SCHEMBL10584714 | 0.78 | CA1 (0.70) | CA1CA2CA9CA12HTT | |
| SCHEMBL17324043 | 0.78 | CA1 (0.70) | CA1CA2CA9CA12HTT | |
| SCHEMBL4667780 | 0.77 | KIF11 (0.59) | CA1CA2CA9CA12STS | |
| SCHEMBL6806188 | 0.77 | CA1 (0.68) | CA1CA2CA9CA12SMN1; SMN2 | |
| SCHEMBL9451388 | 0.76 | CA1 (0.67) | CA1CA2CA9CA12SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193250-B1 | PHENYL SULFAMATE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |