Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.54 |
| ▸ | MC4R | P32245 | 1/20 | 0.51 |
| ▸ | MC5R | P33032 | 1/20 | 0.51 |
| ▸ | MC1R | Q01726 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289201 | 1.00 | TDP1 (0.54) | TDP1CTNNB1MC4RMC5RMC1R | |
| SCHEMBL5323915 | 0.87 | TDP1 (0.53) | TDP1CTNNB1MC4RMC5RMC1R | |
| SCHEMBL1927058 | 0.84 | TDP1 (0.57) | TDP1CTNNB1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL29568355 | 0.84 | TDP1 (0.57) | TDP1CTNNB1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2027675 | 0.84 | TDP1 (0.57) | TDP1CTNNB1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL29478371 | 0.84 | TDP1 (0.57) | TDP1CTNNB1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL289220 | 0.84 | TDP1 (0.57) | TDP1CTNNB1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL29478364 | 0.84 | TDP1 (0.57) | TDP1CTNNB1SLC1A3SLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL1926014 | 0.83 | TDP1 (0.56) | TDP1CTNNB1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL4665442 | 0.81 | TACR1 (0.48) | TDP1CTNNB1SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070258899-A1 | Diagnostic and therapeutic agents | KARYON-CTT LTD (FI) | 2007-11-08 | — | — | US | disclosed |
| WO-2007113385-A1 | DIAGNOSTIC AND THERAPEUTIC AGENTS | KARYON-CTT LTD (FI) | 2007-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070258899-A1 | Diagnostic and therapeutic agents | YBX1, MLX, TPX2 | TDP1 3112/4885CTNNB1 1398/4885MC4R 993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.