Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 4/20 | 0.55 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.55 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | CPB1 | P15086 | 1/20 | 0.33 |
| ▸ | ABAT | P80404 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1905712 | 1.00 | GRIK1 (0.55) | GRIK1GRIK2EP300CPB1ABAT | |
| SCHEMBL984850 | 0.86 | GRIK1 (0.58) | GRIK1GRIK2EP300APEX1 | |
| SCHEMBL7561363 | 0.85 | EP300 (0.59) | GRIK1GRIK2EP300APEX1 | |
| SCHEMBL8055460 | 0.85 | EP300 (0.59) | GRIK1GRIK2EP300APEX1 | |
| SCHEMBL7173369 | 0.85 | EP300 (0.59) | GRIK1GRIK2EP300APEX1 | |
| SCHEMBL3656820 | 0.83 | GRIK1 (0.57) | GRIK1GRIK2EP300CPB1ABAT | |
| SCHEMBL714326 | 0.83 | GRIK1 (0.57) | GRIK1GRIK2EP300CPB1ABAT | |
| SCHEMBL714325 | 0.83 | GRIK1 (0.57) | GRIK1GRIK2EP300CPB1ABAT | |
| SCHEMBL7176279 | 0.83 | EP300 (0.62) | GRIK1EP300APEX1 | |
| SCHEMBL811600 | 0.82 | GRIK1 (0.52) | GRIK1GRIK2EP300ALDH1A1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1743909-B1 | Extrudate containing a coating | REHAU AG & CO (DE) | 2008-05-07 | — | — | EP | disclosed |
| EP-1743909-A1 | Extrudate containing a coating | REHAU AG + Co (DE) | 2007-01-17 | — | — | EP | disclosed |