SCHEMBL4665592

SCHEMBL4665592

COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2cccnc2C(C(C)F)C(OC)C(=O)O)n1

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.48
CDK1 P06493 1/20 0.44
MAPT P10636 3/20 0.38
TP53 P04637 1/20 0.38
GLA P06280 1/20 0.38
KDM4E B2RXH2 1/20 0.35
NPC1 O15118 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP1A2 P05177 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30177573 1.00 GAA (0.48) GAACDK1MAPTTP53GLA
SCHEMBL14366604 0.86 GAA (0.54) GAACDK1MAPTTP53GLA
SCHEMBL3679455 0.85 GAA (0.53) GAACDK1MAPTTP53GLA
SCHEMBL8097780 0.82 GAA (0.50) GAACDK1MAPTTP53GLA
SCHEMBL9888415 0.81 GAA (0.47) GAACDK1MAPTTP53GLA
SCHEMBL6571681 0.80 GAA (0.48) GAACDK1MAPTTP53GLA
SCHEMBL7456515 0.79 GAA (0.53) GAACDK1MAPTTP53GLA
SCHEMBL15427726 0.79 GAA (0.47) GAACDK1MAPTTP53GLA
SCHEMBL28422175 0.79 GAA (0.47) GAACDK1MAPTTP53GLA
SCHEMBL8539298 0.79 GAA (0.51) GAACDK1MAPTTP53GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3236749-B1 LIQUID TRIBENURON-CONTAINING HERBICIDAL COMPOSITIONS MITSUI AGRISCIENCE INT S A /N V (IE) 2019-07-03 EP disclosed
EP-2144879-B1 PYRIDON CARBOXAMIDES, AGENTS CONTAINING THESE BUT NOT IMPACTING USEFUL PLANTS AND METHOD FOR THEIR MANUFACTURE AND APPLICATION BAYER IP GMBH (DE) 2015-04-08 EP disclosed
US-8198214-B2 Solid formulation BAYER CROPSCIENCE AG (DE) 2012-06-12 US disclosed
EP-1987718-A1 Utilisation of pyridine-2-oxy-3-carbon amides as safener Bayer CropScience AG (DE) 2008-11-05 EP disclosed
EP-1987717-A1 Pyridon carboxamides, agents containing these but not impacting useful plants and method for their manufacture and application Bayer CropScience AG (DE) 2008-11-05 EP disclosed
US-20070066487-A1 Solid formulation BAYER CROPSCIENCE GMBH (DE) 2007-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070066487-A1 Solid formulation SMS, SRM, STS GAA 1622/4885CDK1 2814/4885MAPT 3265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.