SCHEMBL466562

SCHEMBL466562

C=CCCC(CN)C1CCCCC1

nearest known ligand 0.48

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.48
ALDH1A1 P00352 1/20 0.46
TP53 P04637 1/20 0.41
KDM4E B2RXH2 1/20 0.39
GMNN O75496 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
SHBG P04278 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL466710 0.81 EPHX1 (0.34) EPHX1ALDH1A1TP53KDM4EGMNN
SCHEMBL1615544 0.77 ALDH1A1 (0.53) EPHX1ALDH1A1TP53KDM4EGMNN
SCHEMBL4379254 0.76 EPHX1 (0.62) EPHX1ALDH1A1TP53KDM4EGMNN
SCHEMBL25265236 0.76 EPHX1 (0.41) EPHX1ALDH1A1TP53KDM4EGMNN
SCHEMBL25193077 0.76 EPHX1 (0.41) EPHX1ALDH1A1TP53KDM4EGMNN
SCHEMBL11519202 0.74 ALDH1A1 (0.50) EPHX1ALDH1A1TP53KDM4EGMNN
SCHEMBL17215700 0.74 TSHR (0.42) EPHX1ALDH1A1SHBG
SCHEMBL25264998 0.74 EPHX1 (0.38) EPHX1TP53KDM4EGMNNLMNA
SCHEMBL25194833 0.74 EPHX1 (0.38) EPHX1TP53KDM4EGMNNLMNA
SCHEMBL3429556 0.73 EPHX1 (0.39) EPHX1ALDH1A1TP53KDM4EGMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8877857-B2 Polar group-containing copolymer, rubber composition and studless tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-11-04 US disclosed
EP-2404944-B1 POLAR GROUP-CONTAINING COPOLYMER, RUBBER COMPOSITION AND STUDLESS TIRE SUMITOMO RUBBER IND (JP) 2014-05-14 EP disclosed
CN-102365306-B Polar group-containing copolymer, rubber composition and studless tire SUMITOMO RUBBER IND 2014-04-02 CN disclosed
US-20120095153-A1 POLAR GROUP-CONTAINING COPOLYMER, RUBBER COMPOSITION AND STUDLESS TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2012-04-19 US disclosed
CN-102365306-A Polar group-containing copolymer, rubber composition and studless tire SUMITOMO RUBBER IND 2012-02-29 CN disclosed
EP-2404944-A1 POLAR GROUP-CONTAINING COPOLYMER, RUBBER COMPOSITION AND STUDLESS TIRE Sumitomo Rubber Industries, Ltd. (JP) 2012-01-11 EP disclosed