Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SHBG | P04278 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1615544 | 0.98 | ALDH1A1 (0.53) | ALDH1A1EPHX1TP53KDM4EGMNN | |
| SCHEMBL11515656 | 0.95 | ALDH1A1 (0.45) | ALDH1A1EPHX1TP53KDM4EGMNN | |
| SCHEMBL1397282 | 0.87 | EPHX1 (0.50) | ALDH1A1EPHX1TP53KDM4EGMNN | |
| SCHEMBL4379254 | 0.81 | EPHX1 (0.62) | ALDH1A1EPHX1TP53KDM4EGMNN | |
| SCHEMBL8114464 | 0.81 | ALDH1A1 (0.47) | ALDH1A1EPHX1TP53KDM4EGMNN | |
| SCHEMBL13767350 | 0.79 | SHBG (0.48) | ALDH1A1EPHX1TP53KDM4EGMNN | |
| SCHEMBL16281688 | 0.78 | ALDH1A1 (0.44) | ALDH1A1EPHX1TP53KDM4EGMNN | |
| SCHEMBL29007633 | 0.76 | EPHX1 (0.40) | ALDH1A1EPHX1TP53KDM4EGMNN | |
| SCHEMBL19608947 | 0.75 | ALDH1A1 (0.55) | ALDH1A1EPHX1TP53KDM4EGMNN | |
| SCHEMBL19335696 | 0.75 | ALDH1A1 (0.50) | ALDH1A1EPHX1TP53KDM4EGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154931-A | Process for the preparation of cyclic ureas | THE UPJOHN COMPANY (US) | 1979-05-15 | — | — | US | disclosed |