Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 10/20 | 0.39 |
| ▸ | BCR | P11274 | 10/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 2/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4665682 | 0.85 | ABL1 (0.38) | ALDH1A1MAPTABL1BCR | |
| SCHEMBL4667504 | 0.85 | BPTF (0.51) | ABL1BCRGSK3BHTR6 | |
| Formic Acid SCHEMBL4663967 | 0.85 | NR1I2 (0.40) | ALDH1A1MAPTABL1BCRNR1I2 | |
| Formic Acid SCHEMBL4666063 | 0.84 | NR1I2 (0.46) | ALDH1A1MAPTNR1I2PTPN2PTPN1 | |
| Formic Acid SCHEMBL4665624 | 0.84 | HTR6 (0.46) | GAAALDH1A1MAPTABL1BCR | |
| Formic Acid SCHEMBL4664322 | 0.83 | NR1I2 (0.37) | ALDH1A1MAPTABL1BCRNR1I2 | |
| Formic Acid SCHEMBL4667521 | 0.82 | HTR6 (0.46) | GAAALDH1A1MAPTABL1BCR | |
| Formic Acid SCHEMBL4664307 | 0.81 | HTR6 (0.51) | GAAALDH1A1MAPTABL1BCR | |
| SCHEMBL4664297 | 0.81 | HTR6 (0.54) | ABL1BCRGSK3BHTR6 | |
| Formic Acid SCHEMBL4664367 | 0.78 | ABL1 (0.41) | ALDH1A1LMNAMAPTABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | ALTANA PHARMA AG (DE) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | MAP3K19, MAP3K6, MAP3K20 | HTT 3296/4885GAA 3665/4885ALOX12 4672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.