Formic Acid

Formic Acid

SCHEMBL4664367

COc1ccc(S(=O)(=O)Nc2ccc(Nc3cc(-c4ccc5c(ccn5CCCN5CCCC5)c4)ncn3)cc2)cc1.O=CO

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 7/20 0.41
BCR P11274 7/20 0.41
KIT P10721 1/20 0.41
HTR6 P50406 2/20 0.41
HRH3 Q9Y5N1 1/20 0.41
TP53 P04637 1/20 0.40
NPC1 O15118 1/20 0.40
GSK3B P49841 2/20 0.39
ACP1 P24666 1/20 0.39
ALDH1A1 P00352 3/20 0.39
MAPT P10636 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL4665807 0.96 HTR6 (0.44) ABL1BCRKITHTR6GSK3B
Formic Acid SCHEMBL4666206 0.95 ABL1 (0.41) ABL1BCRKITHTR6GSK3B
Formic Acid SCHEMBL4666096 0.93 PAX8 (0.43) KITHTR6HRH3GSK3BACP1
Formic Acid SCHEMBL4665737 0.92 LMNA (0.42) ABL1BCRKITHTR6GSK3B
Formic Acid SCHEMBL4667472 0.89 PAX8 (0.44) KITHTR6TP53GSK3BALDH1A1
Formic Acid SCHEMBL4666146 0.88 HTR6 (0.38) KITHTR6GSK3BALDH1A1MAPT
Formic Acid SCHEMBL4665624 0.88 HTR6 (0.46) ABL1BCRHTR6GSK3BALDH1A1
Formic Acid SCHEMBL4666082 0.87 HRH3 (0.53) ABL1BCRKITHRH3MAPT
Formic Acid SCHEMBL4666026 0.87 GSK3B (0.42) ABL1BCRGSK3BALDH1A1LMNA
Formic Acid SCHEMBL4667521 0.87 HTR6 (0.46) ABL1BCRHTR6GSK3BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080242681-A1 N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors ALTANA PHARMA AG (DE) 2008-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080242681-A1 N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors MAP3K19, MAP3K6, MAP3K20 ABL1 24/4885BCR 402/4885KIT 675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.