Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38183 | 0.91 | — | — | |
| SCHEMBL5477839 | 0.88 | — | — | |
| SCHEMBL16566929 | 0.88 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL6015163 | 0.88 | — | — | |
| SCHEMBL6015087 | 0.88 | — | — | |
| SCHEMBL27974492 | 0.88 | — | — | |
| SCHEMBL4266363 | 0.88 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL12616548 | 0.78 | — | — | |
| SCHEMBL4665692 | 0.77 | — | — | |
| SCHEMBL3405080 | 0.76 | MAPK1 (0.32) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603924-B1 | ALCOHOLATES OF RARE EARTH MTALS A PRECURSORS FOR METALOXIDES LAYERS OR FILMS | SIGMA ALDRICH CO (US) | 2008-06-04 | — | — | EP | claimed |