Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 5/20 | 0.44 |
| ▸ | FDPS | P14324 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 9/20 | 0.38 |
| ▸ | CA1 | P00915 | 8/20 | 0.38 |
| ▸ | CA9 | Q16790 | 8/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | CA7 | P43166 | 4/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.38 |
| ▸ | CA3 | P07451 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12980209 | 1.00 | SMPD1 (0.44) | SMPD1FDPSCA2CA1CA9 | |
| SCHEMBL10588891 | 1.00 | SMPD1 (0.44) | SMPD1FDPSCA2CA1CA9 | |
| SCHEMBL4953366 | 1.00 | SMPD1 (0.44) | SMPD1FDPSCA2CA1CA9 | |
| SCHEMBL6320654 | 0.96 | SMPD1 (0.42) | SMPD1FDPSCA2CA1CA9 | |
| SCHEMBL5181675 | 0.94 | SMPD1 (0.43) | SMPD1FDPSCA2CA1CA9 | |
| SCHEMBL9157001 | 0.93 | SMPD1 (0.40) | SMPD1FDPSCA2CA1CA9 | |
| SCHEMBL1486848 | 0.92 | FDPS (0.41) | SMPD1FDPSCA2CA1CA9 | |
| Sulfuric Acid SCHEMBL4319267 | 0.88 | FDPS (0.50) | SMPD1FDPSCA2CA1GGPS1 | |
| Sulfuric Acid SCHEMBL6405447 | 0.88 | FDPS (0.50) | SMPD1FDPSCA2CA1GGPS1 | |
| Sulfuric Acid SCHEMBL9766385 | 0.88 | FDPS (0.50) | SMPD1FDPSCA2CA1GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8409554-B2 | Aqueous mixture of a mono C14-C22 trimethylammonium cationic surfactant, a di-(C20-C24) imidazoline quaternary surfactant, and a mono C12-C22 alkyl hydroxyethyl dimethylammonium surfactant; hair conditioners; smoothness, softness, manageability, cuticle integrity, antistatic agents and shine | CONOPCO, INC. (US) | 2013-04-02 | — | — | US | disclosed |
| US-20080233070-A1 | Hair Treatment Compositions | CONOPCO, INC. D/B/A UNILEVER | 2008-09-25 | — | — | US | disclosed |
| EP-1680075-B1 | HAIR CONDITIONING COMPOSITIONS | UNILEVER PLC (GB) | 2008-01-02 | — | — | EP | disclosed |
| EP-1725212-B1 | HAIR TREATMENT COMPOSITIONS | UNILEVER PLC (GB) | 2007-06-27 | — | — | EP | disclosed |
| EP-1725212-A1 | HAIR TREATMENT COMPOSITIONS | UNILEVER PLC (GB) | 2006-11-29 | — | — | EP | disclosed |
| EP-1680075-A1 | HAIR CONDITIONING COMPOSITIONS | UNILEVER PLC (GB) | 2006-07-19 | — | — | EP | disclosed |
| US-20050232892-A1 | Hair conditioning composition | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2005-10-20 | — | — | US | disclosed |
| WO-2005089702-A1 | HAIR TREATMENT COMPOSITIONS | UNILEVER PLC (GB) | 2005-09-29 | — | — | WO | disclosed |
| WO-2005039517-A1 | HAIR CONDITIONING COMPOSITIONS | UNILEVER PLC (GB) | 2005-05-06 | — | — | WO | disclosed |
| EP-1515689-A1 | HAIR CONDITIONING COMPOSITION | UNILEVER PLC (GB) | 2005-03-23 | — | — | EP | disclosed |
| WO-2004000250-A1 | HAIR CONDITIONING COMPOSITION | UNILEVER PLC (GB) | 2003-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050232892-A1 | Hair conditioning composition | H1-10, SLC9A1, ASH2L | SMPD1 1104/4885FDPS 4873/4885CA2 740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.