Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.42 |
| ▸ | PPARA | Q07869 | 6/20 | 0.42 |
| ▸ | PPARD | Q03181 | 5/20 | 0.42 |
| ▸ | TPH1 | P17752 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4666690 | 0.78 | PPARA (0.54) | PPARGPPARAPPARDEPHX2PTGES | |
| SCHEMBL4666261 | 0.78 | FFAR1 (0.40) | PDE4APDE4BPDE4CPDE4DHIF1A | |
| SCHEMBL3217512 | 0.78 | BRD4 (0.41) | PDE4BPARP15PARP10FFAR1 | |
| SCHEMBL3213102 | 0.76 | CNR1 (0.38) | PPARGPPARAPPARDEPHX2PDE4A | |
| SCHEMBL3211241 | 0.76 | PARP15 (0.36) | PPARGPPARAPPARDEPHX2PDE4A | |
| SCHEMBL3202842 | 0.74 | HDAC8 (0.43) | PPARGPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3202826 | 0.74 | HDAC8 (0.43) | PPARGPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4632439 | 0.72 | PDE4D (0.42) | EPHX2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27716262 | 0.71 | FDPS (0.43) | PPARGPDE4B | |
| SCHEMBL3217588 | 0.71 | PPARG (0.59) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |