Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.40 |
| ▸ | PDE4A | P27815 | 5/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | AGER | Q15109 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4666693 | 0.78 | FFAR1 (0.48) | FFAR1KDM4EMETKMT2A | |
| SCHEMBL4666259 | 0.78 | PPARG (0.42) | FFAR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3202842 | 0.74 | HDAC8 (0.43) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL3202826 | 0.74 | HDAC8 (0.43) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL4632439 | 0.72 | PDE4D (0.42) | PDE4APDE4BPDE4CPDE4DHIF1A | |
| SCHEMBL3217512 | 0.71 | BRD4 (0.41) | FFAR1PDE4BALDH1A1TDP1ERBB2 | |
| SCHEMBL27716262 | 0.71 | FDPS (0.43) | PDE4BALDH1A1ERBB2 | |
| SCHEMBL4666766 | 0.70 | TAS1R3 (0.41) | FFAR1 | |
| SCHEMBL3213102 | 0.70 | CNR1 (0.38) | FFAR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3211241 | 0.69 | PARP15 (0.36) | FFAR1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |