Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4664353 | 0.91 | KAT2B (0.34) | KAT2BBAZ2B | |
| Hydrochloric Acid SCHEMBL4668002 | 0.90 | KAT2B (0.33) | KAT2BBAZ2B | |
| SCHEMBL4666526 | 0.82 | PDE4D (0.36) | — | |
| Hydrochloric Acid SCHEMBL4665000 | 0.81 | PDE4D (0.36) | — | |
| SCHEMBL21305857 | 0.76 | KAT2B (0.36) | KAT2BBAZ2B | |
| Hydrochloric Acid SCHEMBL22301617 | 0.75 | KAT2B (0.36) | KAT2BBAZ2B | |
| SCHEMBL14254009 | 0.72 | ELANE (0.42) | KAT2BBAZ2B | |
| Trifluoroacetic Acid SCHEMBL3624786 | 0.71 | GAA (0.34) | — | |
| SCHEMBL23922563 | 0.71 | THRB (0.34) | KAT2BBAZ2B | |
| SCHEMBL20455701 | 0.70 | KAT2B (0.36) | SYKKAT2BBAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1395551-B1 | HYDROXY ALKYL AMINE DERIVATIVES AS BETA-SECRETASE INHIBITORS AND THEIR USE FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND SIMILAR DISEASES | ELAN PHARM INC (US) | 2008-05-21 | — | — | EP | disclosed |
| US-20070299263-A1 | Hydroxy Alkyl Amines | Elan Pharmaceuticals, Inc. and Pharmacia & Upjohn Company | 2007-12-27 | — | — | US | disclosed |
| US-7144897-B2 | Hydroxy alkyl amines | Elan Oharmaceuticals, Inc. (US) | 2006-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299263-A1 | Hydroxy Alkyl Amines | MAOA, PSEN2, PSEN1 | SYK 3313/4885KAT2B 351/4885BAZ2B 2829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.