SCHEMBL4666386

SCHEMBL4666386

O=C(O)CCC1COCCN1

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 3/20 0.38
MALT1 Q9UDY8 1/20 0.33
HTT P42858 1/20 0.32
GLA P06280 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16771700 1.00 ARG1 (0.38) ARG1MALT1HTTGLA
SCHEMBL16771693 1.00 ARG1 (0.38) ARG1MALT1HTTGLA
Hydrochloric Acid SCHEMBL15573124 0.98 ARG1 (0.38) ARG1MALT1HTTGLA
Hydrochloric Acid SCHEMBL16759537 0.98 ARG1 (0.38) ARG1MALT1HTTGLA
Hydrochloric Acid SCHEMBL18259318 0.98 ARG1 (0.38) ARG1MALT1HTTGLA
Hydrochloric Acid SCHEMBL20453849 0.86 ARG1 (0.38) ARG1
SCHEMBL2380650 0.84 ARG1 (0.35) ARG1MALT1
SCHEMBL1854210 0.84 ARG1 (0.38) ARG1MALT1
SCHEMBL30301492 0.84 ARG1 (0.38) ARG1MALT1
Hydrochloric Acid SCHEMBL11540995 0.82 ARG1 (0.37) ARG1MALT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240226287-A1 NOVEL LIPID COMPOUND AND LIPID NANOPARTICLE COMPOSITION COMPRISING THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2024-07-11 US disclosed
EP-3122747-B1 DIHYDROPYRIMIDINE COMPOUNDS AND THEIR APPLICATION IN PHARMACEUTICALS NORTH & SOUTH BROTHER PHARMACY INVESTMENT CO LTD (CN) 2020-05-20 EP disclosed
EP-3074394-B1 PROCESSES FOR PREPARING DIHYDROPYRIMIDINE DERIVATIVES AND INTERMEDIATES THEREOF SUNSHINE LAKE PHARMA CO LTD (CN) 2019-02-20 EP disclosed
EP-2007857-A1 USE OF RYLENES AS MARKERS FOR LIQUIDS BASF SE (DE) 2008-12-31 EP disclosed
US-7365067-B2 Indanol derivative SANKYO COMPANY, LIMITED (JP) 2008-04-29 US disclosed
EP-1904497-A1 SUBSTITUTED RYLENE DERIVATIVES BASF SE (DE) 2008-04-02 EP disclosed
WO-2007099059-A1 USE OF RYLENES AS MARKERS FOR LIQUIDS BASF SE (DE) 2007-09-07 WO disclosed
US-20070197570-A1 Indanol derivative SANKYO COMPANY, LIMITED (JP) 2007-08-23 US disclosed
EP-1819678-A1 RYLENE TETRACARBOXYLIC ACID DIIMIDES SUBSTITUTED BY CYCLIC AMINO GROUPS BASF AKTIENGESELLSCHAFT (DE) 2007-08-22 EP disclosed
EP-1746095-A1 INDANOL DERIVATIVE Sankyo Company, Limited (JP) 2007-01-24 EP disclosed
EP-1355903-A1 PYRAZOLE DERIVATIVES AGAINST TGF OVEREXPRESSION GLAXO GROUP LIMITED (GB) 2003-10-29 EP disclosed
WO-2002066462-A1 PYRAZOLE DERIVATIVES AGAINST TGF OVEREXPRESSION GLAXO GROUP LIMITED (GB) 2002-08-29 WO disclosed
EP-0730591-B1 ESTERS OF SUBSTITUTED-HYDROXYACETYL PIPERAZINE PHENYL OXAZOLIDINONES UPJOHN CO (US) 1999-07-14 EP disclosed
US-5763631-A CIS-EPOXIDE COMPOUNDS; ANTIVIRUS AGENTS; USEFUL TO TREAT THE AIDS LUCKY LIMITED (KR) 1998-06-09 US disclosed
US-5744621-A CIS-EPOXIDE COMPOUNDS LUCKY LIMITED. (KR) 1998-04-28 US disclosed
US-5652238-A WATER SOLUBILITY; ANTIMICROBIAL AGENTS EFFECTIVE AGAINST RESISTANT STAPHYLOCOCCI, ENTEROCOCCI, AND STREPTOCOCCI PHARMACIA & UPJOHN COMPANY (US) 1997-07-29 US disclosed
US-5587388-A AIDS; VIRICIDES LUCKY LIMITED (KR) 1996-12-24 US disclosed
EP-0730591-A1 ESTERS OF SUBSTITUTED-HYDROXYACETYL PIPERAZINE PHENYL OXAZOLIDINONES PHARMACIA & UPJOHN COMPANY (US) 1996-09-11 EP disclosed
WO-1995014684-A1 ESTERS OF SUBSTITUTED-HYDROXYACETYL PIPERAZINE PHENYL OXAZOLIDINONES THE UPJOHN COMPANY (US) 1995-06-01 WO disclosed
EP-0601486-A1 Cis-epoxide derivatives useful as irreversible HIV protease inhibitors and process and intermediates for their preparation LUCKY LTD. (KR) 1994-06-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070197570-A1 Indanol derivative BDKRB2, BDKRB1, TACR2 ARG1 229/4885MALT1 3405/4885HTT 3799/4885
US-20240226287-A1 NOVEL LIPID COMPOUND AND LIPID NANOPARTICLE COMPOSITION COMPRISING THE SAME HDLBP, LRAT, CETP ARG1 2781/4885MALT1 4427/4885HTT 2879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.