SCHEMBL4666940

SCHEMBL4666940

O=C(O)Cc1ccc(-c2cc(CCCCCCc3ccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O)c(-c4ccc(CC(=O)O)cc4)c3)ccc2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]2O)cc1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SELP P16109 2/20 0.84
SELPLG Q14242 1/20 0.84
PPARG P37231 2/20 0.58
PPARD Q03181 2/20 0.58
PPARA Q07869 2/20 0.58
SLC28A3 Q9HAS3 2/20 0.51
ACHE P22303 1/20 0.48
DYRK1A Q13627 1/20 0.47
HPGD P15428 2/20 0.46
HSD17B10 Q99714 2/20 0.46
SLC5A1 P13866 2/20 0.46
KDM4E B2RXH2 1/20 0.46
CYP3A4 P08684 1/20 0.46
MAPT P10636 1/20 0.46
THRB P10828 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
SLC28A2 O43868 1/20 0.46
SLC5A2 P31639 1/20 0.46
EPHX2 P34913 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bimosiamose SCHEMBL26341832 0.91 SELP (1.00) SELPSELPLGPPARGPPARDPPARA
Bimosiamose SCHEMBL14015902 0.91 SELP (1.00) SELPSELPLGPPARGPPARDPPARA
Bimosiamose SCHEMBL29372538 0.91 SELP (1.00) SELPSELPLGPPARGPPARDPPARA
Bimosiamose SCHEMBL14970212 0.91 SELP (1.00) SELPSELPLGPPARGPPARDPPARA
Bimosiamose SCHEMBL12182030 0.91 SELP (1.00) SELPSELPLGPPARGPPARDPPARA
Bimosiamose SCHEMBL2529148 0.91 SELP (1.00) SELPSELPLGPPARGPPARDPPARA
SCHEMBL7614341 0.91 SELP (1.00) SELPSELPLGPPARGPPARDPPARA
SCHEMBL7620761 0.91 SELP (1.00) SELPSELPLGPPARGPPARDPPARA
Bimosiamose SCHEMBL29367817 0.91 SELP (1.00) SELPSELPLGPPARGPPARDPPARA
Bimosiamose SCHEMBL2528669 0.90 SELP (0.98) SELPSELPLGPPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080249107-A1 Non-Glycosylated/Non-Glycosidic/Non-Peptidic Small Molecule Psgl-1 Mimetics for the Treatment of Inflammatory Disorders REVOTAR BIOPHARMACEUTICALS AG (DE) 2008-10-09 US disclosed
EP-1577289-A1 Non-glycosylated/-glycosidic/-peptidic small molecule selectin inhibitors for the treament of inflammatory disorders Revotar Biopharmaceuticals AG (DE) 2005-09-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080249107-A1 Non-Glycosylated/Non-Glycosidic/Non-Peptidic Small Molecule Psgl-1 Mimetics for the Treatment of Inflammatory Disorders SELP, SELPLG, SELE SELP 1/4885SELPLG 2/4885PPARG 1449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.