Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 15/20 | 0.53 |
| ▸ | DHODH | Q02127 | 5/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4668016 | 0.89 | ADORA1 (0.53) | ADORA1DHODHADORA3 | |
| SCHEMBL14600200 | 0.89 | ADORA1 (0.51) | ADORA1DHODHADORA3ADORA2B | |
| SCHEMBL4668528 | 0.88 | ADORA1 (0.53) | ADORA1DHODHADORA3 | |
| SCHEMBL4666257 | 0.85 | ADORA1 (0.48) | ADORA1DHODHADORA3 | |
| SCHEMBL14600448 | 0.82 | ADORA1 (0.43) | ADORA1DHODHADORA2B | |
| SCHEMBL4667046 | 0.80 | ADORA1 (0.52) | ADORA1ADORA3ADORA2B | |
| SCHEMBL4633959 | 0.80 | ADORA1 (0.44) | ADORA1DHODHADORA2B | |
| SCHEMBL4666215 | 0.78 | ADORA1 (0.51) | ADORA1DHODHADORA3 | |
| SCHEMBL14600263 | 0.77 | ADORA1 (0.49) | ADORA1DHODHADORA3 | |
| SCHEMBL4669467 | 0.76 | ADORA1 (0.49) | ADORA1DHODHADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928455-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | Bayer Healthcare, LLC (US) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |