Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4667142 | 1.00 | CASP3 (0.49) | CASP3CASP1KMT2AMDM4TP53 | |
| SCHEMBL799761 | 0.86 | MDM4 (0.51) | CASP3CASP1MDM4TP53CTSL | |
| SCHEMBL29444635 | 0.86 | MDM4 (0.51) | CASP3CASP1MDM4TP53CTSL | |
| SCHEMBL29511478 | 0.86 | MDM4 (0.51) | CASP3CASP1MDM4TP53CTSL | |
| SCHEMBL6790172 | 0.86 | MDM4 (0.51) | CASP3CASP1MDM4TP53CTSL | |
| SCHEMBL3725892 | 0.86 | MDM4 (0.51) | CASP3CASP1MDM4TP53CTSL | |
| SCHEMBL30182933 | 0.86 | MDM4 (0.51) | CASP3CASP1MDM4TP53CTSL | |
| SCHEMBL118132 | 0.84 | CASP3 (0.53) | CASP3CASP1KMT2AMDM4TP53 | |
| SCHEMBL4667137 | 0.84 | CASP3 (0.53) | CASP3CASP1KMT2AMDM4TP53 | |
| SCHEMBL118115 | 0.84 | CASP3 (0.53) | CASP3CASP1KMT2AMDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1985612-A1 | Arymethylen substituted N-Acyl-gamma-aminoalcohols | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-10-29 | — | — | EP | disclosed |