Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30182933 | 1.00 | MDM4 (0.51) | MDM4TP53CTSLCTSSCTSK | |
| SCHEMBL29511478 | 1.00 | MDM4 (0.51) | MDM4TP53CTSLCTSSCTSK | |
| SCHEMBL6790172 | 1.00 | MDM4 (0.51) | MDM4TP53CTSLCTSSCTSK | |
| SCHEMBL799761 | 1.00 | MDM4 (0.51) | MDM4TP53CTSLCTSSCTSK | |
| SCHEMBL3725892 | 1.00 | MDM4 (0.51) | MDM4TP53CTSLCTSSCTSK | |
| SCHEMBL6019567 | 0.87 | CTSS (0.68) | CTSLCTSSCTSK | |
| SCHEMBL4667145 | 0.86 | CASP3 (0.49) | MDM4TP53CTSLCTSSCTSK | |
| SCHEMBL4667142 | 0.86 | CASP3 (0.49) | MDM4TP53CTSLCTSSCTSK | |
| SCHEMBL6019561 | 0.84 | CTSL (0.49) | MDM4TP53CTSLCTSSCTSK | |
| SCHEMBL6019553 | 0.84 | CTSL (0.53) | MDM4TP53CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115068469-B | TIGIT inhibitors and uses thereof | 深圳市小分子新药创新中心有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-115068469-A | TIGIT inhibitor and application thereof | 深圳市小分子新药创新中心有限公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-113912670-B | Angiotensin converting enzyme 2 inhibitor, application thereof and anti-coronavirus infection drug | 深圳市小分子新药创新中心有限公司 | 2022-04-08 | — | — | CN | disclosed |