Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.37 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7251136 | 0.89 | HTT (0.42) | TSHRKDM4EGLACASP3SENP8 | |
| SCHEMBL4669924 | 0.87 | KDM4E (0.41) | KDM4EGLACASP3SENP8SENP7 | |
| SCHEMBL7254543 | 0.87 | RECQL (0.47) | TSHRKDM4ESMN1; SMN2MAPTHSP90AA1 | |
| SCHEMBL4668106 | 0.86 | ALDH1A1 (0.43) | KDM4EGLAMAPTALDH1A1GAA | |
| SCHEMBL4668080 | 0.86 | KDM4E (0.38) | KDM4EGLACASP3SENP8SENP7 | |
| SCHEMBL4668875 | 0.85 | PTK2 (0.37) | KDM4EGLACASP3SENP8SENP7 | |
| SCHEMBL7256864 | 0.84 | L3MBTL1 (0.46) | TSHRKDM4EGLACASP3SENP8 | |
| SCHEMBL4668120 | 0.84 | MEN1 (0.53) | KDM4EGLAMAPTMAPK1ALDH1A1 | |
| SCHEMBL7250882 | 0.83 | HPGD (0.39) | TSHRKDM4EGLACASP3SENP8 | |
| SCHEMBL4669206 | 0.83 | NPSR1 (0.40) | KDM4EGLACASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129689-B1 | Keratinous fiber dyeing composition comprising N-(2-hydroxybenzene)-carbamate or N-(2-hydroxybenzene)urea derivatives as coupling agents and process for dyeing | OREAL (FR) | 2008-07-09 | — | — | EP | claimed |