Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17102719 | 0.80 | ALDH1A1 (0.45) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 | |
| SCHEMBL6939459 | 0.79 | POLB (0.45) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 | |
| Hydrochloric Acid SCHEMBL6943412 | 0.78 | POLB (0.47) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 | |
| SCHEMBL4668038 | 0.78 | ALDH1A1 (0.42) | ALDH1A1CYP3A4TSHRHTTLMNA | |
| SCHEMBL2739262 | 0.74 | ALDH1A1 (0.59) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 | |
| Sulfuric Acid SCHEMBL8535837 | 0.73 | ALDH1A1 (0.49) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 | |
| SCHEMBL15938784 | 0.73 | SMN1; SMN2 (0.48) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 | |
| SCHEMBL29212507 | 0.72 | ALDH1A1 (0.52) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 | |
| SCHEMBL3939407 | 0.72 | ALDH1A1 (0.44) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 | |
| SCHEMBL30879400 | 0.72 | ALDH1A1 (0.44) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129689-B1 | Keratinous fiber dyeing composition comprising N-(2-hydroxybenzene)-carbamate or N-(2-hydroxybenzene)urea derivatives as coupling agents and process for dyeing | OREAL (FR) | 2008-07-09 | — | — | EP | claimed |