Sulfuric Acid

Sulfuric Acid

SCHEMBL8535837

COc1cc(N(C)C)ccc1N.O=S(=O)(O)O

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A known ✓ P04350 1/20 0.41
TUBB known ✓ P07437 1/20 0.41
TUBA3C known ✓ P0DPH7 1/20 0.41
TUBA1B known ✓ P68363 1/20 0.41
TUBA4A known ✓ P68366 1/20 0.41
TUBB4B known ✓ P68371 1/20 0.41
TUBB3 known ✓ Q13509 1/20 0.41
TUBB2A known ✓ Q13885 1/20 0.41
TUBB8 known ✓ Q3ZCM7 1/20 0.41
TUBA3E known ✓ Q6PEY2 1/20 0.41
TUBA1A known ✓ Q71U36 1/20 0.41
TUBA1C known ✓ Q9BQE3 1/20 0.41
TUBB6 known ✓ Q9BUF5 1/20 0.41
TUBB2B known ✓ Q9BVA1 1/20 0.41
TUBB1 known ✓ Q9H4B7 1/20 0.41
TLR9 known ✓ Q9NR96 1/20 0.38
ALDH1A1 P00352 6/20 0.49
CYP3A4 P08684 3/20 0.49
HSD17B10 Q99714 3/20 0.47
TSHR P16473 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2739262 0.89 ALDH1A1 (0.59) ALDH1A1CYP3A4HSD17B10TSHRTDP1
SCHEMBL3105597 0.81 NSD2 (0.36) ALDH1A1CYP3A4HSD17B10TSHRTDP1
Sulfuric Acid SCHEMBL7805762 0.80 KDM4E (0.50) ALDH1A1CYP3A4HSD17B10TSHRTDP1
SCHEMBL25032417 0.80 ALDH1A1 (0.49) ALDH1A1CYP3A4HSD17B10TSHRTDP1
Sulfuric Acid SCHEMBL29558859 0.79 ALDH1A1 (0.53) ALDH1A1CYP3A4HSD17B10TSHRTDP1
Sulfuric Acid SCHEMBL3340873 0.79 ALDH1A1 (0.53) ALDH1A1CYP3A4HSD17B10TSHRTDP1
Sulfuric Acid SCHEMBL7630472 0.79 ALDH1A1 (0.77) ALDH1A1CYP3A4HSD17B10TSHRTDP1
Sulfuric Acid SCHEMBL8765503 0.77 ALDH1A1 (0.52) ALDH1A1CYP3A4HSD17B10TSHRTDP1
Sulfuric Acid SCHEMBL8500882 0.77 ALDH1A1 (0.45) ALDH1A1CYP3A4HSD17B10TSHRTDP1
SCHEMBL151204 0.77 APAF1 (0.37) ALDH1A1CYP3A4HSD17B10TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0630642-B1 Naphthol couplers BRISTOL MYERS SQUIBB CO (US) 1998-08-12 EP claimed
EP-0630642-A1 Naphthol couplers Bristol-Myers Company (US) 1994-12-28 EP claimed
US-5344463-A OXIDATION CLAIROL, INC. (US) 1994-09-06 US claimed
EP-0630642-B1 Naphthol couplers BRISTOL MYERS SQUIBB CO (US) 1998-08-12 EP disclosed
EP-0630642-A1 Naphthol couplers Bristol-Myers Company (US) 1994-12-28 EP disclosed
US-5344463-A OXIDATION CLAIROL, INC. (US) 1994-09-06 US disclosed
US-5183941-A Aminophenol CLAIROL INCORPORATED (US) 1993-02-02 US disclosed
US-5073173-A Oxidative hair dye mixture CLAIROL INCORPORATED (US) 1991-12-17 US disclosed
EP-0398702-A2 Dye couplers Bristol-Myers Squibb Company (US) 1990-11-22 EP disclosed
US-4248591-A HAIR DYES L'OREAL (FR) 1981-02-03 US disclosed
US-4221729-A HAIR DYES L'OREAL (FR) 1980-09-09 US disclosed
US-3977825-A Indoanilines in keratinic fiber dye cmpositions L'OREAL (FR) 1976-08-31 US disclosed