Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 4/20 | 0.37 |
| ▸ | BCR | P11274 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4666185 | 0.92 | LMNA (0.43) | LMNAKITABL1BCRMAPT | |
| Formic Acid SCHEMBL4665686 | 0.90 | ABL1 (0.40) | LMNAKITABL1BCRTP53 | |
| Formic Acid SCHEMBL4664235 | 0.90 | GSK3B (0.40) | ABL1BCREGFRTNNI3K | |
| Formic Acid SCHEMBL4665746 | 0.87 | LMNA (0.45) | LMNAKITABL1BCRMAPT | |
| SCHEMBL4667453 | 0.86 | ABL1 (0.34) | ABL1BCRMAPTTP53EGFR | |
| Formic Acid SCHEMBL4666169 | 0.86 | HTR6 (0.46) | LMNAKITCCNT1CDK9EGFR | |
| Formic Acid SCHEMBL4663792 | 0.86 | SGK1 (0.39) | ABL1BCR | |
| Formic Acid SCHEMBL4664274 | 0.86 | EGFR (0.45) | LMNAKITMAPTTP53CCNT1 | |
| Formic Acid SCHEMBL4665800 | 0.86 | PRF1 (0.39) | KITABL1BCRTP53 | |
| Formic Acid SCHEMBL4665883 | 0.86 | LMNA (0.44) | LMNAKITABL1BCRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | ALTANA PHARMA AG (DE) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | MAP3K19, MAP3K6, MAP3K20 | LMNA 4261/4885KIT 675/4885ABL1 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.