Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRF1 | P14222 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | BCR | P11274 | 2/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL4663835 | 0.96 | AXL (0.40) | PRF1PIK3CAEGFRMETMERTK | |
| Formic Acid SCHEMBL4663893 | 0.94 | HTR6 (0.40) | PRF1PIK3CAEGFRABL1BCR | |
| Formic Acid SCHEMBL4665681 | 0.94 | HTR7 (0.37) | PRF1PIK3CAEGFRHTR7MET | |
| Formic Acid SCHEMBL4665709 | 0.92 | HTR6 (0.39) | EGFRMETMERTKAXLABL1 | |
| Formic Acid SCHEMBL4666035 | 0.91 | PRF1 (0.41) | PRF1PIK3CAABL1BCRPIK3R1 | |
| Formic Acid SCHEMBL4666078 | 0.90 | HTR6 (0.40) | PRF1PIK3CAABL1BCRPIK3R1 | |
| Formic Acid SCHEMBL4665800 | 0.89 | PRF1 (0.39) | PRF1PIK3CAABL1BCRPIK3R1 | |
| Formic Acid SCHEMBL4664032 | 0.89 | HTR6 (0.39) | PRF1PIK3CAEGFRHTR7ABL1 | |
| Formic Acid SCHEMBL4666168 | 0.89 | ABL1 (0.38) | EGFRMETAXLABL1BCR | |
| Formic Acid SCHEMBL4665754 | 0.88 | AXL (0.39) | METMERTKAXLABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | ALTANA PHARMA AG (DE) | 2008-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242681-A1 | N-4-(6-(Hetero)Aryl-Pyrimidin-4-Ylaminophenyl)-Benzenesulfonamides as Kinase Inhibitors | MAP3K19, MAP3K6, MAP3K20 | PRF1 3924/4885PIK3CA 161/4885EGFR 279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.