SCHEMBL4667745

SCHEMBL4667745

N#Cc1ccc(-c2ccc(OS(N)(=O)=O)cc2)c(C#N)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
STS P08842 11/20 1.00
CA2 P00918 5/20 0.64
CA9 Q16790 5/20 0.64
CA1 P00915 4/20 0.64
CYP19A1 P11511 13/20 0.56
CA12 O43570 2/20 0.50
KIF11 P52732 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4667722 0.91 STS (0.84) STSCA2CA9CA1CYP19A1
SCHEMBL4667727 0.86 STS (0.75) STSCA2CA9CA1CYP19A1
SCHEMBL4666114 0.86 STS (0.75) STSCA2CA9CA1CYP19A1
SCHEMBL4665450 0.81 CA2 (0.89) STSCA2CA9CA1CYP19A1
SCHEMBL4665452 0.81 STS (0.68) STSCA2CA9CA1CYP19A1
SCHEMBL4668665 0.81 STS (0.68) STSCA2CA9CA1CYP19A1
SCHEMBL4667728 0.81 STS (0.68) STSCA2CA9CA1CYP19A1
SCHEMBL4667754 0.80 STS (0.67) STSCA2CA9CA1CYP19A1
SCHEMBL4667771 0.80 STS (0.67) STSCA2CA9CA1CYP19A1
SCHEMBL9451286 0.79 CA2 (1.00) STSCA2CA9CA1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 EP disclosed
WO-2024168301-A2 PERSONALIZED CRISPR PROFILING FOR CANCER FUNCTION ONCOLOGY, INC. (US) 2024-08-15 WO disclosed
EP-1193250-B1 PHENYL SULFAMATE DERIVATIVES TEIKOKU HORMONE MFG CO LTD (JP) 2008-06-04 EP disclosed
US-6762205-B1 STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION TEIKOKU HORMONE MFG. CO., LTD. (JP) 2004-07-13 US disclosed
EP-1193250-A1 PHENYL SULFAMATE DERIVATIVES Teikoku Hormone Mfg. Co., Ltd. (JP) 2002-04-03 EP disclosed