Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 7/20 | 0.67 |
| ▸ | CA2 | P00918 | 8/20 | 0.58 |
| ▸ | CA9 | Q16790 | 8/20 | 0.58 |
| ▸ | CA1 | P00915 | 7/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4665389 | 0.87 | STS (0.50) | STSCA2CA9CA1CYP19A1 | |
| SCHEMBL4666136 | 0.85 | CA1 (0.52) | STSCA2CA9CA1CYP19A1 | |
| SCHEMBL6800482 | 0.84 | LMNA (0.47) | STSCA2CA9CA1CYP19A1 | |
| SCHEMBL4666173 | 0.82 | CYP19A1 (0.55) | STSCA2CA9CA1CYP19A1 | |
| SCHEMBL8140554 | 0.82 | VCAM1 (0.60) | VCAM1ALDH1A1LMNAPTGS2 | |
| SCHEMBL4667304 | 0.82 | CA2 (0.65) | STSCA2CA9CA1CA12 | |
| SCHEMBL4668707 | 0.82 | XDH (0.52) | VCAM1ALDH1A1LMNA | |
| SCHEMBL4667745 | 0.80 | STS (1.00) | STSCA2CA9CA1CYP19A1 | |
| SCHEMBL4667727 | 0.80 | STS (0.75) | STSCA2CA9CA1CYP19A1 | |
| SCHEMBL4667729 | 0.78 | CA2 (0.89) | STSCA2CA9CA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193250-B1 | PHENYL SULFAMATE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |