Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 6/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7166038 | 0.93 | NPC1 (0.39) | NPC1GAASMN1; SMN2MAPTROCK2 | |
| SCHEMBL4667681 | 0.82 | CYP19A1 (0.59) | SMN1; SMN2MAPTALDH1A1TDP1CYP19A1 | |
| SCHEMBL30847362 | 0.81 | ALDH1A1 (0.56) | NPC1GAASMN1; SMN2MAPTBRD4 | |
| SCHEMBL4521276 | 0.81 | ALDH1A1 (0.56) | NPC1GAASMN1; SMN2MAPTBRD4 | |
| SCHEMBL6157990 | 0.80 | ALDH1A1 (0.50) | GAAMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25692523 | 0.79 | MAPK8 (0.44) | NPC1GAASMN1; SMN2MAPTROCK2 | |
| SCHEMBL4667768 | 0.78 | GAA (0.40) | NPC1GAASMN1; SMN2MAPTROCK2 | |
| SCHEMBL7170222 | 0.78 | CYP19A1 (0.53) | SMN1; SMN2MAPTALDH1A1TDP1CYP19A1 | |
| SCHEMBL7163970 | 0.77 | LMNA (0.49) | NPC1GAASMN1; SMN2MAPTBRD4 | |
| SCHEMBL4667844 | 0.77 | ALDH1A1 (0.46) | GAAMAPTROCK2CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203762-B1 | Cationic oxidation bases, their use for oxidation dyeing of keratin fibres, dyeing compositions and dyeing methods | OREAL (FR) | 2008-07-02 | — | — | EP | disclosed |
| EP-0968171-B1 | CATIONIC OXIDATION BASES, THEIR USE FOR OXIDATION DYEING OF KERATIN FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | OREAL (FR) | 2003-10-08 | — | — | EP | disclosed |
| EP-1203762-A2 | Cationic oxidation bases, their use for oxidation dyeing of keratin fibres, dyeing compositions and dyeing methods | L'OREAL (FR) | 2002-05-08 | — | — | EP | disclosed |
| EP-0968171-A1 | NOVEL CATIONIC OXIDATION BASES, THEIR USE FOR OXIDATION DYEING OF KERATIN FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | L'OREAL (FR) | 2000-01-05 | — | — | EP | disclosed |
| WO-1999003819-A1 | NOVEL CATIONIC OXIDATION BASES, THEIR USE FOR OXIDATION DYEING OF KERATIN FIBRES, DYEING COMPOSITIONS AND DYEING METHODS | L'OREAL (FR) | 1999-01-28 | — | — | WO | disclosed |