SCHEMBL4667865

SCHEMBL4667865

CC(CCc1ccccc1)=C(C)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.64
KEAP1 Q14145 1/20 0.57
FFAR1 O14842 2/20 0.53
HDAC2 Q92769 2/20 0.50
HDAC8 Q9BY41 2/20 0.50
HDAC6 Q9UBN7 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
KDM4E B2RXH2 2/20 0.49
KMT2A Q03164 2/20 0.49
RECQL P46063 1/20 0.49
HDAC1 Q13547 2/20 0.48
HDAC3 O15379 1/20 0.48
MAPK1 P28482 1/20 0.48
ADRA1A P35348 1/20 0.48
HDAC4 P56524 1/20 0.48
SLC6A3 Q01959 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
HDAC7 Q8WUI4 1/20 0.48
HDAC10 Q969S8 1/20 0.48
HDAC11 Q96DB2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19656197 0.79 ALDH1A1 (0.58) ALDH1A1KEAP1FFAR1HDAC2HDAC8
SCHEMBL10700398 0.79 CES1 (0.54) ALDH1A1HDAC8HDAC6KDM4EKMT2A
SCHEMBL10932286 0.79 CES1 (0.54) ALDH1A1HDAC8HDAC6KDM4EKMT2A
SCHEMBL2876835 0.79 CES1 (0.54) ALDH1A1HDAC8HDAC6KDM4EKMT2A
SCHEMBL9876476 0.79 ALDH1A1 (0.61) ALDH1A1KEAP1FFAR1HDAC2HDAC8
Benzylacetone SCHEMBL1346 0.79 ALDH1A1 (1.00) ALDH1A1KEAP1FFAR1HDAC2HDAC8
SCHEMBL6450584 0.78 ALDH1A1 (0.56) ALDH1A1KEAP1FFAR1HDAC2HDAC8
SCHEMBL6450577 0.78 ALDH1A1 (0.56) ALDH1A1KEAP1FFAR1HDAC2HDAC8
Acetic Acid SCHEMBL27883812 0.78 ALDH1A1 (0.67) ALDH1A1KEAP1FFAR1HDAC2HDAC8
Benzylacetone SCHEMBL23581088 0.77 ALDH1A1 (0.95) ALDH1A1KEAP1FFAR1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108003972-B Lubricating oil composition for diesel engine and preparation method thereof 中国石油化工股份有限公司 2020-10-27 CN disclosed
US-20160003805-A1 METHODS FOR IDENTIFYING ARTHROPOD REPELLENTS AND ATTRACTANTS, AND COMPOUNDS AND COMPOSITIONS IDENTIFIED BY SUCH METHODS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-01-07 US disclosed
EP-1941870-A2 Perfume Composition comprising perilla aldehyde Shiseido Co., Ltd. (JP) 2008-07-09 EP disclosed
US-7169746-B2 Perfume composition SHISEIDO CO., LTD. (JP) 2007-01-30 US disclosed
US-20040242452-A1 For effecting mental control through psycho-sedation or psycho-stimulation SHISEIDO COMPANY, LTD. (JP) 2004-12-02 US disclosed
EP-1424071-A1 PERFUME COMPOSITIONS SHISEIDO COMPANY LIMITED (JP) 2004-06-02 EP disclosed