Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.46 |
| ▸ | HTR2A known ✓ | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C known ✓ | P28335 | 1/20 | 0.46 |
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.46 |
| ▸ | DRD3 known ✓ | P35462 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL28210913 | 1.00 | HDAC1 (0.52) | HDAC1HDAC2FFAR3HDAC3HDAC8 | |
| Succinic Acid SCHEMBL28438549 | 1.00 | HDAC1 (0.52) | HDAC1HDAC2FFAR3HDAC3HDAC8 | |
| Succinic Acid SCHEMBL28276766 | 0.93 | HDAC1 (0.46) | HDAC1HDAC2FFAR3HDAC3HDAC8 | |
| Adipic Acid SCHEMBL27696357 | 0.93 | FFAR4 (0.59) | FFAR4FFAR1LMNAALDH1A1TDP1 | |
| Butyric Acid SCHEMBL27916950 | 0.92 | HDAC1 (0.65) | HDAC1HDAC2FFAR3HDAC3HDAC8 | |
| Succinic Acid SCHEMBL28829567 | 0.91 | TP53 (0.48) | HDAC1HDAC2FFAR3HDAC3HDAC8 | |
| Levulinic Acid SCHEMBL28753020 | 0.91 | LMNA (0.61) | HDAC1HDAC2FFAR3HDAC3HDAC8 | |
| Adipic Acid SCHEMBL437561 | 0.91 | FFAR4 (0.57) | FFAR4FFAR1ALDH1A1TDP1AKR1B1 | |
| Succinic Acid SCHEMBL28210832 | 0.91 | HDAC1 (0.44) | HDAC1HDAC2FFAR3HDAC3HDAC8 | |
| Glutarate SCHEMBL8153856 | 0.90 | FFAR4 (0.55) | HDAC1HDAC2FFAR3HDAC3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 713 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025128433-A1 | MELT-SPUN THERMOPLASTIC POLYURETHANE FIBER AND FABRIC MADE THEREFROM | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2025-06-19 | — | — | WO | claimed |
| CN-116285273-B | Full-biodegradable material with balanced toughness and preparation method thereof | 会通新材料股份有限公司 | 2025-05-30 | — | — | CN | claimed |
| CN-120059154-A | In C4Method for producing polybutylene succinate polyester by taking unsaturated binary oxygen-containing compound as raw material | 上海师范大学 | 2025-05-30 | — | — | CN | claimed |
| CN-120040741-A | Method and process system for producing poly (butylene succinate) by using gaseous crude maleic anhydride | 上海师范大学 | 2025-05-27 | — | — | CN | claimed |
| CN-119524215-A | Degradable anti-adhesion material and preparation method thereof | 上海发微医用材料有限公司 | 2025-02-28 | — | — | CN | claimed |
| CN-119505190-A | Metal ion hybridized degradable polyester, and preparation method and application thereof | 广东粤港澳大湾区黄埔材料研究院 | 2025-02-25 | — | — | CN | claimed |
| WO-2025027340-A2 | A COMPONENT FOR AN AEROSOL PROVISION ARTICLE | Nicoventures Trading Limited (GB) | 2025-02-06 | — | — | WO | claimed |
| WO-2025022101-A1 | AEROSOL PROVISION SYSTEM | Nicoventures Trading Limited (GB) | 2025-01-30 | — | — | WO | claimed |
| CN-118879048-A | High-strength high-impact high-heat-resistance polylactic acid composite material, preparation method and application | 安徽金普瑞新材料有限公司 | 2024-11-01 | — | — | CN | claimed |
| EP-4164428-B1 | A COMPONENT FOR A DELIVERY SYSTEM | BRITISH AMERICAN TOBACCO INVESTMENTS LTD (GB) | 2024-09-11 | — | — | EP | claimed |
| US-20150107613-A1 | SMOKING ARTICLE FILTERS | BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) | 2015-04-23 | — | — | US | claimed |
| US-20150090282-A1 | SMOKING ARTICLE FILTERS | BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (US) | 2015-04-02 | — | — | US | claimed |
| EP-2844092-A1 | IMPROVEMENTS IN SMOKING ARTICLE FILTERS | British American Tobacco (Investments) Limited (GB) | 2015-03-11 | — | — | EP | claimed |
| EP-2844093-A1 | IMPROVEMENTS IN SMOKING ARTICLE FILTERS | British American Tobacco (Investments) Ltd (GB) | 2015-03-11 | — | — | EP | claimed |
| CN-104270971-A | Improvements in smoking article filters | BRITISH AMERICAN TOBACCO CO | 2015-01-07 | — | — | CN | claimed |
| CN-104270972-A | Improvements in smoking article filters | BRITISH AMERICAN TOBACCO CO | 2015-01-07 | — | — | CN | claimed |
| WO-2013164623-A1 | IMPROVEMENTS IN SMOKING ARTICLE FILTERS | BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) | 2013-11-07 | — | — | WO | claimed |
| WO-2013164626-A1 | IMPROVEMENTS IN SMOKING ARTICLE FILTERS | BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) | 2013-11-07 | — | — | WO | claimed |
| CN-103147230-A | Fully-degradable bird-repelling agricultural non-woven fabric and preparation method for same | UNIV WUHAN TEXTILE | 2013-06-12 | — | — | CN | claimed |
| CN-101760037-A | Completely degraded plant powder modified thermoplastics composite material and preparation method thereof | KINGFA SCIENCE & TECHNOLOGY CO | 2010-06-30 | — | — | CN | claimed |