Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9878020 | 0.81 | SCN9A (0.53) | SCN9AXIAPBIRC2NOS3NOS2 | |
| SCHEMBL13802927 | 0.79 | SCN9A (0.43) | SCN9AXIAPBIRC2NOS3NOS2 | |
| SCHEMBL29466334 | 0.72 | MAPT (0.72) | SCN9ARAB9AKDM4EMAPTMEN1 | |
| SCHEMBL7346798 | 0.72 | MAPT (0.72) | SCN9ARAB9AKDM4EMAPTMEN1 | |
| SCHEMBL4665629 | 0.71 | SCN9A (0.61) | SCN9AXIAPBIRC2NOS3NOS2 | |
| SCHEMBL18655885 | 0.70 | — | — | |
| SCHEMBL24011004 | 0.69 | SCN9A (0.55) | SCN9AXIAPBIRC2NOS3NOS2 | |
| SCHEMBL690670 | 0.69 | — | — | |
| SCHEMBL15699050 | 0.68 | KCNH2 (0.41) | SCN9AXIAPBIRC2NOS3NOS2 | |
| SCHEMBL4667411 | 0.68 | SCN9A (0.46) | SCN9AXIAPBIRC2NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1982749-B1 | Novel hair colouring compositions for use in oxidative hair dyeing | PROCTER & GAMBLE (US) | 2013-04-17 | — | — | EP | claimed |
| EP-1982749-A2 | Novel hair colouring compositions for use in oxidative hair dyeing | The Procter and Gamble Company (US) | 2008-10-22 | — | — | EP | claimed |
| US-7303592-B2 | Hair coloring compositions for use in oxidative hair dyeing | THE PROCTER & GAMBLE COMPANY (US) | 2007-12-04 | — | — | US | claimed |
| EP-1855644-A2 | HAIR COLORING COMPOSITIONS FOR USE IN OXIDATIVE HAIR DYEING | The Procter and Gamble Company (US) | 2007-11-21 | — | — | EP | claimed |
| WO-2006099115-A2 | HAIR COLORING COMPOSITIONS FOR USE IN OXIDATIVE HAIR DYEING | THE PROCTER & GAMBLE COMPANY (US) | 2006-09-21 | — | — | WO | claimed |
| US-20050188480-A1 | Novel hair coloring compositions for use in oxidative hair dyeing | WELLA OPERATIONS US, LLC | 2005-09-01 | — | — | US | claimed |
| EP-1982749-B1 | Novel hair colouring compositions for use in oxidative hair dyeing | PROCTER & GAMBLE (US) | 2013-04-17 | — | — | EP | disclosed |
| EP-1982748-A2 | Novel hair colouring compositions for use in oxidative hair dyeing | The Procter & Gamble (US) | 2008-10-22 | — | — | EP | disclosed |
| EP-1982749-A2 | Novel hair colouring compositions for use in oxidative hair dyeing | The Procter and Gamble Company (US) | 2008-10-22 | — | — | EP | disclosed |
| US-7303592-B2 | Hair coloring compositions for use in oxidative hair dyeing | THE PROCTER & GAMBLE COMPANY (US) | 2007-12-04 | — | — | US | disclosed |
| EP-1855644-A2 | HAIR COLORING COMPOSITIONS FOR USE IN OXIDATIVE HAIR DYEING | The Procter and Gamble Company (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006099115-A2 | HAIR COLORING COMPOSITIONS FOR USE IN OXIDATIVE HAIR DYEING | THE PROCTER & GAMBLE COMPANY (US) | 2006-09-21 | — | — | WO | disclosed |
| US-20050188480-A1 | Novel hair coloring compositions for use in oxidative hair dyeing | WELLA OPERATIONS US, LLC | 2005-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050188480-A1 | Novel hair coloring compositions for use in oxidative hair dyeing | COXFA4L2, TYR, GPX4 | SCN9A 1395/4885XIAP 3001/4885BIRC2 3502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.