Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 4/20 | 0.41 |
| ▸ | PREP | P48147 | 3/20 | 0.36 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27889024 | 0.87 | PLA2G2A (0.42) | PLA2G2APREPCELA1ALDH1A1MAPT | |
| SCHEMBL27789996 | 0.84 | PLA2G2A (0.40) | PLA2G2APREPCELA1ALDH1A1MAPT | |
| SCHEMBL2003295 | 0.78 | PLA2G2A (0.51) | PLA2G2A | |
| SCHEMBL27789955 | 0.78 | PLA2G2A (0.60) | PLA2G2AALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL4668204 | 0.76 | PLA2G2A (0.50) | PLA2G2AMTNR1AMTNR1B | |
| SCHEMBL27789956 | 0.75 | PLA2G2A (0.48) | PLA2G2AALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL27768508 | 0.73 | PLA2G2A (0.40) | PLA2G2A | |
| SCHEMBL27889115 | 0.72 | PLA2G2A (0.40) | PLA2G2AALDH1A1MAPTLMNAKDM4E | |
| SCHEMBL27790041 | 0.70 | S1PR3 (0.37) | PREPCELA1ALDH1A1MAPTLMNA | |
| SCHEMBL2002183 | 0.68 | PLA2G2A (0.49) | PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931632-A2 | USEFUL INDOLE COMPOUNDS | Microbia Inc. (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007022501-A2 | USEFUL INDOLE COMPOUNDS | MICROBIA, INC. (US) | 2007-02-22 | — | — | WO | disclosed |