Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 6/20 | 0.40 |
| ▸ | MIF | P14174 | 6/20 | 0.38 |
| ▸ | CD74 | P04233 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.36 |
| ▸ | YWHAH | Q04917 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27789956 | 0.90 | PLA2G2A (0.48) | PLA2G2AS1PR3 | |
| SCHEMBL27789996 | 0.89 | PLA2G2A (0.40) | PLA2G2AS1PR3YWHAH | |
| SCHEMBL27768594 | 0.83 | S1PR3 (0.46) | PLA2G2AMIFCD74CYP3A4S1PR3 | |
| SCHEMBL27905705 | 0.83 | S1PR3 (0.46) | PLA2G2AMIFCD74CYP3A4S1PR3 | |
| SCHEMBL27768472 | 0.83 | PLA2G2A (0.36) | PLA2G2AS1PR3BRD4 | |
| SCHEMBL4666719 | 0.83 | CYP3A4 (0.37) | PLA2G2AMIFCD74CYP3A4S1PR3 | |
| SCHEMBL2012404 | 0.81 | PLA2G2A (0.43) | PLA2G2AMIFCD74S1PR3YWHAH | |
| SCHEMBL2004847 | 0.79 | PLA2G2A (0.49) | PLA2G2AMIFS1PR3YWHAH | |
| SCHEMBL27789967 | 0.76 | S1PR3 (0.53) | PLA2G2AS1PR3 | |
| SCHEMBL27768492 | 0.76 | S1PR3 (0.53) | PLA2G2AS1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102850324-A | Indole compounds | MICROBIA INC | 2013-01-02 | — | — | CN | disclosed |
| CN-101563337-A | Indole compounds | MICROBIA INC (US) | 2009-10-21 | — | — | CN | disclosed |